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用于纸质数字微流控芯片的导电电极和介电薄膜的低成本制造

Affordable Fabrication of Conductive Electrodes and Dielectric Films for a Paper-based Digital Microfluidic Chip.

作者信息

Soum Veasna, Kim Yunpyo, Park Sooyong, Chuong Mary, Ryu Soo Ryeon, Lee Sang Ho, Tanev Georgi, Madsen Jan, Kwon Oh-Sun, Shin Kwanwoo

机构信息

Department of Chemistry, Institute of Biological Interfaces, Sogang University, Seoul 04107, Korea.

Department of Chemical Engineering, The Cooper Union for Advancement of Science and Art, New York, NY 10003, USA.

出版信息

Micromachines (Basel). 2019 Feb 7;10(2):109. doi: 10.3390/mi10020109.

Abstract

In order to fabricate a digital microfluidic (DMF) chip, which requires a patterned array of electrodes coated with a dielectric film, we explored two simple methods: Ballpoint pen printing to generate the electrodes, and wrapping of a dielectric plastic film to coat the electrodes. For precise and programmable printing of the patterned electrodes, we used a digital plotter with a ballpoint pen filled with a silver nanoparticle (AgNP) ink. Instead of using conventional material deposition methods, such as chemical vapor deposition, printing, and spin coating, for fabricating the thin dielectric layer, we used a simple method in which we prepared a thin dielectric layer using pre-made linear, low-density polyethylene (LLDPE) plastic (17-μm thick) by simple wrapping. We then sealed it tightly with thin silicone oil layers so that it could be used as a DMF chip. Such a treated dielectric layer showed good electrowetting performance for a sessile drop without contact angle hysteresis under an applied voltage of less than 170 V. By using this straightforward fabrication method, we quickly and affordably fabricated a paper-based DMF chip and demonstrated the digital electrofluidic actuation and manipulation of drops.

摘要

为了制造数字微流控(DMF)芯片,该芯片需要有涂覆介电膜的图案化电极阵列,我们探索了两种简单方法:用圆珠笔打印来生成电极,以及用介电塑料膜包裹来涂覆电极。为了精确且可编程地打印图案化电极,我们使用了一台配备填充有银纳米颗粒(AgNP)墨水的圆珠笔的数字绘图仪。对于制造薄介电层,我们没有使用诸如化学气相沉积、印刷和旋涂等传统材料沉积方法,而是采用了一种简单方法,即通过简单包裹用预制的线性低密度聚乙烯(LLDPE)塑料(17微米厚)制备薄介电层。然后我们用薄硅油层将其紧密密封,使其可用作DMF芯片。在小于170V的施加电压下,这种处理过的介电层对静止液滴表现出良好的电润湿性能,且无接触角滞后现象。通过使用这种直接的制造方法,我们快速且经济地制造出了基于纸的DMF芯片,并展示了液滴的数字电流体驱动和操控。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a89/6412519/510652b8fa97/micromachines-10-00109-g001.jpg

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