Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea.
Allergy Asthma Immunol Res. 2009 Oct;1(1):45-7. doi: 10.4168/aair.2009.1.1.45. Epub 2009 Sep 25.
Bovine serum albumin (BSA), which is present in bovine plasma, is one of the major allergens affecting patients with food allergies induced by milk and meat. It is also commonly used in research laboratories. Although some reports have documented food allergies associated with BSA, BSA-induced occupational asthma has not been reported. We report a case of occupational asthma and rhinitis in a laboratory worker caused by the inhalation of BSA powder, in which an IgE-mediated response was suggested as the pathogenic mechanism.
牛血清白蛋白(BSA)存在于牛血浆中,是引起由牛奶和肉类诱发的食物过敏的主要过敏原之一。它也常用于研究实验室。尽管有一些报告记录了与 BSA 相关的食物过敏,但尚未报道 BSA 引起的职业性哮喘。我们报告了一例实验室工作人员因吸入 BSA 粉末引起的职业性哮喘和鼻炎病例,其中提示 IgE 介导的反应是致病机制。