Parker Erica, Judge Melinda A, Macete Eusebio, Nhampossa Tacilta, Dorward Jienchi, Langa Denise C, Schacht Caroline De, Couto Aleny, Vaz Paula, Vitoria Marco, Molfino Lucas, Idowu Rachel T, Bhatt Nilesh, Naniche Denise, Le Souëf Peter N
Faculty of Health and Medical Sciences, The University of Western Australia, Perth, Australia.
Manhiça Health Research Centre, Manhiça, Mozambique.
South Afr J HIV Med. 2021 May 28;22(1):1237. doi: 10.4102/sajhivmed.v22i1.1237. eCollection 2021.
The burden of HIV is especially concerning for Eastern and Southern Africa (ESA), as despite expansion of test-and-treat programmes, this region continues to experience significant challenges resulting from high rates of morbidity, mortality and new infections. Hard-won lessons from programmes on the ground in ESA should be shared.
This report summarises relevant evidence and regional experts' recommendations regarding challenges specific to ESA.
This commentary includes an in-depth review of relevant literature, progress against global goals and consensus opinion from experts.
Recommendations include priorities for essential research (surveillance data collection, key and vulnerable population education and testing, in-country testing trials and evidence-based support services to improve retention in care) as well as research that can accelerate progress towards the prevention of new infections and achieving ambitious global goals in ESA.
The elimination of HIV in ESA will require continued investment, commitment to evidence-based programmes and persistence. Local research is critical to ensuring that responses in ESA are targeted, efficient and evaluated.
尽管检测与治疗项目有所扩大，但东非和南部非洲（ESA）的艾滋病毒负担尤其令人担忧，该地区仍因高发病率、高死亡率和新感染率而面临重大挑战。应分享在ESA实地项目中来之不易的经验教训。
本报告总结了与ESA特有的挑战相关的证据和区域专家的建议。
本评论包括对相关文献的深入回顾、在实现全球目标方面取得的进展以及专家的共识意见。
建议包括基础研究的优先事项（监测数据收集、关键和脆弱人群教育与检测、国内检测试验以及基于证据的支持服务以提高治疗依从性）以及能够加速ESA预防新感染进程并实现宏伟全球目标的研究。
在ESA消除艾滋病毒需要持续投资、致力于基于证据的项目以及坚持不懈。本地研究对于确保ESA的应对措施具有针对性、高效性并得到评估至关重要。
