Center for Social Epidemiology and Population Health, Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109, USA.
Am J Infect Control. 2010 May;38(4):251-8. doi: 10.1016/j.ajic.2009.12.007. Epub 2010 Mar 12.
In June 2006, the Centers for Disease Control and Prevention released a request for applications to identify, improve, and evaluate the effectiveness of nonpharmaceutical interventions (NPIs)-strategies other than vaccines and antiviral medications-to mitigate the spread of pandemic influenza within communities and across international borders (RFA-CI06-010). These studies have provided major contributions to seasonal and pandemic influenza knowledge. Nonetheless, key concerns were identified related to the acceptability and protective efficacy of NPIs. Large-scale intervention studies conducted over multiple influenza epidemics, as well as smaller studies in controlled laboratory settings, are needed to address the gaps in the research on transmission and mitigation of influenza in the community setting. The current novel influenza A (H1N1) pandemic underscores the importance of influenza research.
2006 年 6 月，疾病控制与预防中心发布了一份申请，旨在确定、改进和评估非药物干预措施（NPI）的有效性——除疫苗和抗病毒药物以外的策略——以减轻大流行性流感在社区和国际边界内的传播（RFA-CI06-010）。这些研究为季节性和大流行性流感知识做出了重大贡献。尽管如此，与 NPI 的可接受性和保护效果相关的一些关键问题仍有待解决。需要在多个流感流行期间开展大规模干预研究，并在受控的实验室环境中开展较小规模的研究，以填补社区环境中流感传播和减轻研究方面的空白。当前的新型甲型 H1N1 流感大流行凸显了流感研究的重要性。
