基于体外黏附和抗炎能力选择双歧杆菌改善小鼠结肠炎。
Selection of bifidobacteria based on adhesion and anti-inflammatory capacity in vitro for amelioration of murine colitis.
机构信息
Institute of Microbiology and Biotechnology, University of Ulm, Ulm, Germany.
出版信息
Appl Environ Microbiol. 2010 May;76(9):3048-51. doi: 10.1128/AEM.03127-09. Epub 2010 Mar 12.
Abstract
Adhesion and anti-inflammatory properties of eight strains of bifidobacteria were tested using the intestinal epithelial cell lines Caco-2, T84, and HT29. Two strains were selected for further assessment of their anti-inflammatory capacity in two murine models of colitis. In vivo results confirmed the high anti-inflammatory capacity of a Bifidobacterium bifidum strain.
摘要
采用 Caco-2、T84 和 HT29 肠上皮细胞系测试了 8 株双歧杆菌的黏附和抗炎特性。选择了两株双歧杆菌进一步评估它们在两种结肠炎小鼠模型中的抗炎能力。体内结果证实了一株双歧杆菌的高抗炎能力。
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