可扩展且高效地合成分枝杆菌内酯核心。
Scalable and efficient synthesis of the mycolactone core.
作者信息
Jackson Katrina L, Li Wenju, Chen Chi-Li, Kishi Yoshito
机构信息
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA.
出版信息
Tetrahedron. 2010 Mar 27;66(13):2263-2272. doi: 10.1016/j.tet.2010.02.010.
Abstract
A highly efficient, scalable, and stereoselective synthesis of the mycolactone core is reported. The synthesis consists of 14 longest linear steps, with 19% overall yield.
摘要
报道了一种高效、可扩展且具有立体选择性的分枝杆菌内酯核心的合成方法。该合成由14个最长线性步骤组成，总产率为19%。
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