Department of Rheumatology and Rehabilitation, Barking Havering and Redbridge University Hospitals NHS Trust, King George Hospital, Barley Lanes, Goodmayes, Essex IG3 8YB, UK.
Clin Rheumatol. 2010 Aug;29(8):869-74. doi: 10.1007/s10067-010-1411-9. Epub 2010 Mar 14.
With the aim of assessing whether the Bath Ankylosing Spondylitis Activity and Function Indices (BASDAI and BASFI) are reliable measures of disease activity and function in patients with spondyloarthritides (SpAs), 341 patients with SpA (representing ankylosing spondylitis (14.5%), psoriatic arthritis (27.3%), enteropathic arthritis (6.3%), reactive arthritis (4.9%), and undifferentiated arthritis (46.5%) were asked to complete the BASDAI and BASFI. They were asked to report what their main problems associated with the disease were from a list of seven symptoms: fatigue, neck pain, upper back pain, lower back pain, stiffness, joint pain or swelling, and pain with pressure on joints. Correlations between the main symptoms experienced by patients with SpAs and the indices, defined by Spearman's correlation coefficient, showed that BASDAI best correlated with neck pain [BASDAI 2 and total BASDAI score correlate strongly (p = 0.003 and 0.001, respectively), and BASDAI 1, 4, and 5 correlate moderately (p = 0.03, 0.02, and 0.01, respectively)], followed by stiffness, upper back pain, pain with pressure, lower back pain, fatigue, and joint pain. Stiffness correlated strongly with nine of ten items on BASFI (BASFI 1 showed moderate correlation, p = 0.01), followed by upper back pain (four of ten items correlated strongly, three of ten correlated moderately), neck pain (three of ten tasks correlated strongly and four of ten correlated moderately), lower back pain (one task correlated strongly, five moderately), joint pain and swelling (four tasks correlated moderately), fatigue (three tasks correlated moderately), and pain with pressure (two tasks correlated moderately). BASDAI and BASFI only partly reflect disease activity and patients' functional capacity in SpAs. An alternate instrument is required to assess SpA disease activity and functional capacity more precisely.
为了评估 Bath 强直性脊柱炎活动和功能指数（BASDAI 和 BASFI）是否是评估脊柱关节炎（SpA）患者疾病活动度和功能的可靠指标，我们对 341 例 SpA 患者（包括强直性脊柱炎（14.5%）、银屑病关节炎（27.3%）、肠病性关节炎（6.3%）、反应性关节炎（4.9%）和未分化关节炎（46.5%））进行了 BASDAI 和 BASFI 问卷调查。他们被要求从七种症状（疲劳、颈部疼痛、上背部疼痛、下背部疼痛、僵硬、关节疼痛或肿胀以及关节压痛）列表中报告与疾病相关的主要问题。Spearman 相关系数显示，SpA 患者的主要症状与指数之间的相关性，BASDAI 与颈部疼痛相关性最强[BASDAI 2 和总 BASDAI 评分相关性很强（p=0.003 和 0.001），BASDAI 1、4 和 5 相关性中度（p=0.03、0.02 和 0.01）]，其次是僵硬、上背部疼痛、压痛、下背部疼痛、疲劳和关节疼痛。僵硬与 BASFI 的十个项目中的九个具有强相关性（BASFI 1 显示中度相关性，p=0.01），其次是上背部疼痛（十个项目中的四个具有强相关性，十个项目中的三个具有中度相关性）、颈部疼痛（十个任务中的三个具有强相关性，四个具有中度相关性）、下背部疼痛（一个任务具有强相关性，五个具有中度相关性）、关节疼痛和肿胀（四个任务具有中度相关性）、疲劳（三个任务具有中度相关性）和压痛（两个任务具有中度相关性）。BASDAI 和 BASFI 仅部分反映了 SpA 患者的疾病活动度和功能能力。需要一种替代的工具来更准确地评估 SpA 的疾病活动度和功能能力。
