国内旅行后时差与皮质醇昼夜节律的关联。
Associations between jet lag and cortisol diurnal rhythms after domestic travel.
机构信息
Department of Psychiatry and Behavioral Neuroscience, University of Chicago, USA.
出版信息
Health Psychol. 2010 Mar;29(2):117-23. doi: 10.1037/a0017865.
OBJECTIVE
Millions of adults in the United States travel abruptly across time zones each year. Nevertheless, the impact of traveling over relatively short distances (across 3 or fewer time zones) on diurnal patterning of typical physiological response patterns has yet to be studied in a large, epidemiological sample.
DESIGN
The current research focuses on 764 middle-aged men comparing variations in diurnal cortisol regulation based on number of time zones traveled eastward or westward the day before.
MAIN OUTCOME MEASURE
Participants provided samples of salivary cortisol at waking, 30-min postwaking, 10 a.m., 3 p.m., and bedtime.
RESULTS
Eastward travel was associated with a steeper salivary cortisol awakening response (p < .01) and lower peak (PEAK) levels of salivary cortisol the next morning (p < .05). Westward travel was associated with lower peak levels of cortisol the next morning (p < .05). Effect sizes for these differences ranged from Cohen's d = .29 to .47. Differences were not present for 2 days in their home environment.
CONCLUSIONS
The results provide evidence that traveling across time zones is associated with diurnal cortisol regulation and should be studied further to understand the subsequent impacts on health and well-being in large national samples.
目的
在美国，每年都有数百万成年人突然跨越时区旅行。然而，在一个大型的流行病学样本中，关于跨越相对较短距离（跨越 3 个或更少的时区）对典型生理反应模式昼夜节律的影响尚未进行研究。
设计
本研究关注的是 764 名中年男性，根据前一天向东或向西跨越的时区数量，比较昼夜皮质醇调节的变化。
主要观察指标
参与者在醒来时、醒来后 30 分钟、上午 10 点、下午 3 点和睡前提供唾液皮质醇样本。
结果
向东旅行与唾液皮质醇觉醒反应（p<.01）更陡峭以及第二天早上唾液皮质醇峰值（PEAK）水平更低（p<.05）有关。向西旅行与第二天早上皮质醇峰值水平较低有关（p<.05）。这些差异的效应大小范围从 Cohen's d =.29 到.47。在他们的家庭环境中，这些差异并不存在两天。
结论
研究结果表明，跨时区旅行与昼夜皮质醇调节有关，应在更大的全国样本中进一步研究，以了解其对健康和幸福感的后续影响。
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