Medicines Monitoring Unit (MEMO), University of Dundee, Dundee and Health Services Research Unit, University of Aberdeen, Aberdeen, UK.
Br J Clin Pharmacol. 2010 Feb;69(2):128-35. doi: 10.1111/j.1365-2125.2009.03561.x.
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT * Recruitment is key to the success of clinical trials. * Many clinical trials fail to achieve adequate recruitment. * Public understanding and engagement in clinical research could be improved. WHAT THIS STUDY ADDS * 'Get Randomised' is the first campaign of its kind in the UK. * It is possible to improve public awareness of clinical research using the media. * Further work is needed to determine whether improved public awareness leads to increased participation in clinical research in the future. AIM To increase public awareness and understanding of clinical research in Scotland. METHODS A generic media campaign to raise public awareness of clinical research was launched in 2008. The 'Get Randomised' campaign was a Scotland-wide initiative led by the University of Dundee in collaboration with other Scottish universities. Television, radio and newspaper advertising showed leading clinical researchers, general practitioners and patients informing the public about the importance of randomised clinical trials (RCTs). 'Get Randomised' was the central message and interested individuals were directed to the http://www.getrandomised.org website for more information. To assess the impact of the campaign, cross-sectional surveys were conducted in representative samples of 1040 adults in Scotland prior to campaign launch and again 6 months later. RESULTS There was an improvement in public awareness of clinical trials following the campaign; 56.7% [95% confidence interval (CI) 51.8, 61.6] of the sample recalled seeing or hearing advertising about RCTs following the campaign compared with 14.8% (10.8, 18.9) prior to the campaign launch (difference = 41.4%; 95% CI for difference 35.6, 48.3; P < 0.01). Of those who recalled the advertising, 49% felt that the main message was that people should take part more in medical research. However, on whether they would personally take part in a clinical trial if asked, there was little difference in response following the campaign ['yes' 31.3% (28.4, 34.1) prior; 30.4% (27.6, 33.2) following; difference =-0.9%; 95% CI for difference -4.8, 3.1%; P= 0.92]. CONCLUSIONS It is possible to raise public awareness of clinical research using the media, but further efforts may be required to influence individuals' decisions to take part in clinical research.
已知信息：
招募：临床试验成功的关键。
许多临床试验未能达到足够的招募人数。
公众对临床研究的理解和参与度可以提高。
研究添加内容：
“随机分组”是英国首个此类运动。
利用媒体提高公众对临床研究的认识是可行的。
需要进一步的工作来确定公众意识的提高是否会导致未来参与临床研究的人数增加。
目的：
方法：
2008 年启动了一项提高公众对临床研究认识的通用媒体运动。
“随机分组”运动是由邓迪大学领导的一项全苏格兰倡议，与其他苏格兰大学合作。
电视、广播和报纸广告展示了主要的临床研究人员、全科医生和患者，向公众宣传随机临床试验 (RCT) 的重要性。“随机分组”是核心信息，有兴趣的个人可以访问 http://www.getrandomised.org 网站以获取更多信息。
为了评估运动的影响，在运动启动前和 6 个月后，对苏格兰 1040 名成年人的代表性样本进行了横断面调查。
结果：
运动后公众对临床试验的认识有所提高；
在运动后，56.7%（95%置信区间 [51.8, 61.6]）的样本回忆起看到或听到有关 RCT 的广告，而在运动前，这一比例为 14.8%（10.8, 18.9）（差异=41.4%；95%置信区间 35.6, 48.3；P<0.01）。
在回忆起广告的人中，有 49%的人认为主要信息是人们应该更多地参与医学研究。
然而，在是否会在被要求时亲自参加临床试验方面，运动后的反应几乎没有差异['是'31.3%（28.4, 34.1）；30.4%（27.6, 33.2）；差异=-0.9%；95%置信区间为-4.8, 3.1%；P=0.92]。
结论：
