Health and Environment, Austrian Institute of Technology, Vienna, Austria.
J Hum Hypertens. 2010 Aug;24(8):498-504. doi: 10.1038/jhh.2010.27. Epub 2010 Mar 18.
In the European Society of Cardiology-European Society of Hypertension guidelines of the year 2007, the consequences of arterial stiffness and wave reflection on cardiovascular mortality have a major role. But the investigators claimed the poor availability of devices/methods providing easy and widely suitable measuring of arterial wall stiffness or their surrogates like augmentation index (AIx) or aortic systolic blood pressure (aSBP). The aim of this study was the validation of a novel method determining AIx and aSBP based on an oscillometric method using a common cuff (ARCSolver) against a validated tonometric system (SphygmoCor). aSBP and AIx measured with the SphygmoCor and ARCSolver method were compared for 302 subjects. The mean age was 56 years with an s.d. of 20 years. At least two iterations were performed in each session. This resulted in 749 measurements. For aSBP the mean difference was -0.1 mm Hg with an s.d. of 3.1 mm Hg. The mean difference for AIx was 1.2% with an s.d. of 7.9%. There was no significant difference in reproducibility of AIx for both methods. The variation estimate of inter- and intraobserver measurements was 6.3% for ARCSolver and 7.5% for SphygmoCor. The ARCSolver method is a novel method determining AIx and aSBP based on an oscillometric system with a cuff. The results agree with common accepted tonometric measurements. Its application is easy and for widespread use.
在 2007 年欧洲心脏病学会-欧洲高血压学会指南中,动脉僵硬和波反射对心血管死亡率的后果具有重要作用。但研究人员声称,提供易于广泛适用的动脉壁僵硬测量设备/方法或其替代物(如增强指数(AIx)或主动脉收缩压(aSBP))的可用性较差。本研究的目的是验证一种新的方法,该方法基于使用普通袖带(ARCSolver)的振荡测量法来确定 AIx 和 aSBP,并与经过验证的张力测量系统(SphygmoCor)进行比较。对 302 名受试者进行了 SphygmoCor 和 ARCSolver 方法测量的 aSBP 和 AIx 的比较。平均年龄为 56 岁,标准差为 20 岁。在每个会话中至少进行了两次迭代。这导致了 749 次测量。对于 aSBP,平均差值为-0.1mmHg,标准差为 3.1mmHg。AIx 的平均差值为 1.2%,标准差为 7.9%。两种方法的 AIx 重复性无显著差异。ARCSolver 和 SphygmoCor 的观察者内和观察者间测量的变异估计值分别为 6.3%和 7.5%。ARCSolver 方法是一种基于袖带的振荡系统来确定 AIx 和 aSBP 的新方法。结果与常用的张力测量结果一致。其应用简单,可广泛使用。