• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Epilepsy after craniotomy and the place of prophylactic anticonvulsant drugs: discussion paper.开颅术后癫痫及预防性抗惊厥药物的作用：讨论文件
J R Soc Med. 1991 Apr;84(4):221-3. doi: 10.1177/014107689108400412.
2
Do prophylactic anticonvulsant drugs alter the pattern of seizures after craniotomy?预防性抗惊厥药物会改变开颅术后的癫痫发作模式吗？
J Neurol Neurosurg Psychiatry. 1992 Sep;55(9):753-7. doi: 10.1136/jnnp.55.9.753.
3
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.抗癫痫药物用于开颅术后癫痫发作的预防。
Cochrane Database Syst Rev. 2020 Apr 28;4(4):CD007286. doi: 10.1002/14651858.CD007286.pub5.
4
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.抗癫痫药物用于开颅术后癫痫发作的预防
Cochrane Database Syst Rev. 2018 May 23;5(5):CD007286. doi: 10.1002/14651858.CD007286.pub4.
5
Risk factors for developing epilepsy after craniotomy in children.儿童开颅术后发生癫痫的危险因素。
Childs Nerv Syst. 2006 Nov;22(11):1441-5. doi: 10.1007/s00381-006-0117-4. Epub 2006 May 30.
6
Antiepileptic drugs as prophylaxis for post-craniotomy seizures.抗癫痫药物用于开颅术后癫痫发作的预防
Cochrane Database Syst Rev. 2015 Mar 4(3):CD007286. doi: 10.1002/14651858.CD007286.pub3.
7
Antiepileptic drugs as prophylaxis for de novo brain tumour-related epilepsy after craniotomy: a systematic review and meta-analysis of harm and benefits.抗癫痫药物预防颅手术后新发脑肿瘤相关癫痫的疗效：系统评价和荟萃分析。
J Neurol Neurosurg Psychiatry. 2019 May;90(5):599-607. doi: 10.1136/jnnp-2018-319609. Epub 2019 Jan 23.
8
Postoperative epilepsy: a double-blind trial of phenytoin after craniotomy.
Lancet. 1980 Feb 23;1(8165):384-6. doi: 10.1016/s0140-6736(80)90941-1.
9
Antiepileptic drugs as prophylaxis for post-craniotomy seizures.抗癫痫药物用于开颅术后癫痫发作的预防。
Cochrane Database Syst Rev. 2013 Feb 28(2):CD007286. doi: 10.1002/14651858.CD007286.pub2.
10
Efficacy and tolerability of levetiracetam versus phenytoin after supratentorial neurosurgery.幕上神经外科手术后左乙拉西坦与苯妥英钠的疗效及耐受性比较
Neurology. 2008 Aug 26;71(9):665-9. doi: 10.1212/01.wnl.0000324624.52935.46.

引用本文的文献

1
Development and external validation of the LEAN score to predict late seizures after intracerebral haemorrhage.用于预测脑出血后迟发性癫痫的LEAN评分的开发与外部验证
Eur Stroke J. 2025 Jul 7:23969873251350882. doi: 10.1177/23969873251350882.
2
A multi-center, open-label, randomized clinical trial evaluating the preventive effect of perampanel on craniotomy-induced epileptogenesis in seizure-naive patients with supratentorial brain tumors: study protocol for a GRAMPAS trial.一项多中心、开放标签、随机临床试验，评估吡仑帕奈对幕上脑肿瘤初发癫痫患者开颅术后癫痫发生的预防作用：GRAMPAS试验的研究方案
Trials. 2024 Dec 24;25(1):849. doi: 10.1186/s13063-024-08693-7.
3
Phenytoin Induced Purple Glove Syndrome: An Effective Management Technique.苯妥英钠所致紫手套综合征：一种有效的处理技术
Hosp Pharm. 2024 Jun;59(3):276-281. doi: 10.1177/00185787231224064. Epub 2024 Jan 28.
4
The Occurrence and Relationship of Postoperative Seizure and de novo Epilepsy after Craniotomy Surgery: A Retrospective Single-Center Cohort Study.开颅手术后癫痫发作与新发癫痫的发生及关系：一项回顾性单中心队列研究
Front Surg. 2022 Apr 19;9:881874. doi: 10.3389/fsurg.2022.881874. eCollection 2022.
5
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.抗癫痫药物用于开颅术后癫痫发作的预防。
Cochrane Database Syst Rev. 2020 Apr 28;4(4):CD007286. doi: 10.1002/14651858.CD007286.pub5.
6
Continuous EEG monitoring after brain tumor surgery.脑肿瘤手术后的连续脑电图监测。
Acta Neurochir (Wien). 2019 Sep;161(9):1835-1843. doi: 10.1007/s00701-019-03982-6. Epub 2019 Jul 6.
7
A late onset adult seizure due to intracerebral needle: case-based update.脑内穿刺针导致的迟发性成人癫痫：基于病例的最新情况
Childs Nerv Syst. 2019 Apr;35(4):593-600. doi: 10.1007/s00381-019-04095-2. Epub 2019 Feb 27.
8
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.抗癫痫药物用于开颅术后癫痫发作的预防
Cochrane Database Syst Rev. 2018 May 23;5(5):CD007286. doi: 10.1002/14651858.CD007286.pub4.
9
Prophylactic Anticonvulsants in Patients Undergoing Craniotomy: A Single-Center Experience.行颅切除术患者的预防性抗惊厥药物：单中心经验。
Med Sci Monit. 2018 Apr 27;24:2578-2582. doi: 10.12659/MSM.908717.
10
Association of Seizure Occurrence with Aneurysm Treatment Modality in Aneurysmal Subarachnoid Hemorrhage Patients.蛛网膜下腔出血患者的发作与动脉瘤治疗方式的相关性。
Neurocrit Care. 2018 Aug;29(1):62-68. doi: 10.1007/s12028-018-0506-z.

本文引用的文献

1
The natural history of postoperative seizures.
Acta Neurochir (Wien). 1981;57(1-2):15-22. doi: 10.1007/BF01665108.
2
The incidence of postoperative seizures.术后癫痫发作的发生率。
Acta Neurochir (Wien). 1981;55(3-4):253-64. doi: 10.1007/BF01808441.
3
The effectiveness of prophylactic anticonvulsants following neurosurgery.神经外科手术后预防性抗惊厥药物的疗效。
Acta Neurochir (Wien). 1983;69(3-4):253-8. doi: 10.1007/BF01401812.
4
Phenytoin and postoperative epilepsy. A double-blind study.苯妥英钠与术后癫痫。一项双盲研究。
J Neurosurg. 1983 May;58(5):672-7. doi: 10.3171/jns.1983.58.5.0672.
5
Anticonvulsant prophylaxis in neurological surgery.神经外科手术中的抗惊厥预防
Neurosurgery. 1985 Sep;17(3):510-7. doi: 10.1227/00006123-198509000-00021.
6
Anticonvulsant prophylaxis in neurosurgery.神经外科手术中的抗惊厥预防
Br J Neurosurg. 1989;3(4):425-7. doi: 10.3109/02688698909002827.
7
Epilepsy after two different neurosurgical approaches to the treatment of ruptured intracranial aneurysm.两种不同神经外科手术方法治疗破裂颅内动脉瘤后的癫痫
J Neurol Neurosurg Psychiatry. 1976 Nov;39(11):1052-6. doi: 10.1136/jnnp.39.11.1052.

开颅术后癫痫及预防性抗惊厥药物的作用：讨论文件

Epilepsy after craniotomy and the place of prophylactic anticonvulsant drugs: discussion paper.

作者信息

Shaw M D, Foy P M

机构信息

Mersey Regional Department of Medical & Surgical Neurology, Walton Hospital, Liverpool.

出版信息

J R Soc Med. 1991 Apr;84(4):221-3. doi: 10.1177/014107689108400412.

DOI:10.1177/014107689108400412
PMID:2027149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1293187/
Abstract

A retrospective study of 1000 patients who had undergone supratentorial neurosurgery and with prolonged follow-up revealed an overall postoperative incidence of epilepsy of 17%. The incidence varied with different pathologies but anticonvulsants given prophylactically in a randomized trial did not significantly alter the incidence. Routine anticonvulsant prophylaxis cannot be recommended.

摘要

一项对1000例接受幕上神经外科手术且随访时间较长的患者的回顾性研究显示，术后癫痫的总体发生率为17%。发生率因不同病理情况而异，但在一项随机试验中预防性给予抗惊厥药物并未显著改变发生率。不建议进行常规抗惊厥药物预防。