Merilahti-Palo R, Lahesmaa R, Granfors K, Gripenberg-Lerche C, Toivanen P
Department of Medical Microbiology, Turku University, Finland.
Scand J Infect Dis. 1991;23(1):55-61. doi: 10.3109/00365549109023375.
The purpose of this study was to evaluate the risk of yersinia infection among butchers. Serum samples were collected from 146 abattoir workers, stratified into 3 groups according to exposure to swine throats and intestines. 100 healthy blood donors were used as controls. Antibodies against Yersinia enterocolitica O:3 and O:9 and Y. pseudotuberculosis I and III were measured using ELISA. Symptoms associated with yersiniosis were recorded in a questionnaire. Antibodies against Y. enterocolitica O:3 were observed more often in the sera of abattoir workers (19%), especially in butchers handling swine throats and intestines (27%), than in the sera of healthy blood donors (10%). During the 6 months preceding this study, 30-40% of the workers reported symptoms of abdominal pains and diarrhoea. However, the symptoms did not correlate with the occurrence of antibodies. One butcher had developed a yersinia-triggered prolonged reactive arthritis. Tonsil samples were collected from 120 pigs to determine the extent of yersinia contamination. Positive isolates were obtained from 54 pigs (45%). Y. enterocolitica O:3 was isolated from 31 pigs and Y. pseudotuberculosis III from 11 pigs. All of these strains shared characteristics typical for virulent strains. We conclude that yersinia infections are an occupational health risk to workers slaughtering swine in the abattoirs.
本研究的目的是评估屠夫感染耶尔森菌的风险。从146名屠宰场工人采集血清样本，根据接触猪咽喉和肠道的情况分为3组。100名健康献血者作为对照。采用酶联免疫吸附测定法检测抗小肠结肠炎耶尔森菌O:3和O:9以及假结核耶尔森菌I和III的抗体。通过问卷记录与耶尔森菌病相关的症状。在屠宰场工人血清中观察到抗小肠结肠炎耶尔森菌O:3抗体的比例（19%）高于健康献血者血清（10%），尤其是处理猪咽喉和肠道的屠夫（27%）。在本研究前的6个月期间，30 - 40%的工人报告有腹痛和腹泻症状。然而，这些症状与抗体的出现并无关联。一名屠夫患上了由耶尔森菌引发的慢性反应性关节炎。从120头猪采集扁桃体样本以确定耶尔森菌污染程度。从54头猪（45%）中获得阳性分离株。从31头猪中分离出小肠结肠炎耶尔森菌O:3，从11头猪中分离出假结核耶尔森菌III。所有这些菌株均具有强毒株的典型特征。我们得出结论，耶尔森菌感染对屠宰场宰杀猪的工人构成职业健康风险。
