Department of Microbiology, Aarupadai Veedu Medical College & Hospital, Pondicherry, India.
Department of Dermatology, Aarupadai Veedu Medical College & Hospital, Pondicherry, India.
J Med Microbiol. 2010 Jun;59(Pt 6):736-739. doi: 10.1099/jmm.0.016485-0. Epub 2010 Mar 18.
Arcanobacterium pyogenes is an established but often unrecognized human pathogen. A. pyogenes may also be misidentified as Arcanobacterium haemolyticum, which gives remarkably similar results in conventional biochemical tests. In this study, we have reported three cases of wound infections associated with A. pyogenes and also on the bacteriological characteristics which are relevant for identification of these isolates. The negative reverse CAMP test, the ability to produce acid from xylose and to hydrolyse gelatin and the positive beta-glucuronidase test clearly differentiated A. pyogenes from other closely related species. All three isolates were uniformly susceptible to penicillin, ampicillin, amoxicillin-clavulanic acid, ceftriaxone and gentamicin, variably susceptible to tetracycline and erythromycin and uniformly resistant to cotrimoxazole. Only a few confirmed cases have been reported throughout the world and therefore the diagnostic evaluation of this organism is emphasized.
化脓隐秘杆菌是一种已被确认但常被忽视的人类病原体。化脓隐秘杆菌也可能被错误鉴定为血弧菌，因为它们在常规生化测试中给出了非常相似的结果。在这项研究中，我们报告了三例与化脓隐秘杆菌相关的伤口感染病例，并介绍了与这些分离株鉴定相关的细菌学特征。负的反向 CAMP 试验、从木糖产酸以及水解明胶和阳性β-葡萄糖醛酸酶试验的能力可将化脓隐秘杆菌与其他密切相关的物种明显区分开来。所有三个分离株对青霉素、氨苄西林、阿莫西林-克拉维酸、头孢曲松和庆大霉素均具有均匀的敏感性，对四环素和红霉素的敏感性各不相同，对复方新诺明则具有均匀的耐药性。全世界只有少数确诊病例的报告，因此强调了对该病原体的诊断评估。
