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1
Physical map of the Saccharomyces cerevisiae genome at 110-kilobase resolution.酿酒酵母基因组110千碱基分辨率的物理图谱。
Genetics. 1991 Apr;127(4):681-98. doi: 10.1093/genetics/127.4.681.
2
Physical maps of the six smallest chromosomes of Saccharomyces cerevisiae at a resolution of 2.6 kilobase pairs.酿酒酵母六条最小染色体的物理图谱，分辨率为2.6千碱基对。
Genetics. 1993 May;134(1):81-150. doi: 10.1093/genetics/134.1.81.
3
Chromosome III of Saccharomyces cerevisiae: an ordered clone bank, a detailed restriction map and analysis of transcripts suggest the presence of 160 genes.酿酒酵母的第三条染色体：一个有序克隆文库、一份详细的限制性酶切图谱以及转录本分析表明存在160个基因。
Yeast. 1990 Sep-Oct;6(5):383-401. doi: 10.1002/yea.320060504.
4
Mapping of the trifunctional fatty acid synthetase gene FAS2 on chromosome XVI of Saccharomyces cerevisiae.酿酒酵母十六号染色体上三功能脂肪酸合成酶基因FAS2的定位
Yeast. 1990 Sep-Oct;6(5):411-5. doi: 10.1002/yea.320060506.
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Mapping of the Saccharomyces cerevisiae CDC3, CDC25, and CDC42 genes to chromosome XII by chromosome blotting and tetrad analysis.通过染色体印迹法和四分体分析将酿酒酵母的CDC3、CDC25和CDC42基因定位到第十二号染色体上。
Yeast. 1987 Dec;3(4):243-53. doi: 10.1002/yea.320030405.
6
Alignment of Sfi I sites with the Not I restriction map of Schizosaccharomyces pombe genome.粟酒裂殖酵母基因组的Not I限制性酶切图谱中Sfi I位点的比对。
Nucleic Acids Res. 1991 Nov 25;19(22):6289-94. doi: 10.1093/nar/19.22.6289.
7
Establishing the Cryptosporidium parvum karyotype by NotI and SfiI restriction analysis and Southern hybridization.通过NotI和SfiI限制性分析及Southern杂交确定微小隐孢子虫核型。
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Copy number and chromosomal location of Saccharomyces cerevisiae tRNA(Trp)-encoding genes.酿酒酵母色氨酸编码基因的拷贝数和染色体定位。
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9
Meiotic chromosome condensation and pairing in Saccharomyces cerevisiae studied by chromosome painting.通过染色体描绘研究酿酒酵母中的减数分裂染色体凝聚和配对。
Chromosoma. 1992 Oct;101(10):590-5. doi: 10.1007/BF00360535.
10
Positional mapping of genes by chromosome blotting and chromosome fragmentation.
Methods Enzymol. 1991;194:57-77. doi: 10.1016/0076-6879(91)94007-y.

引用本文的文献

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Meiotic Crossover Patterning.减数分裂交叉模式
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Genome-wide toxicogenomic study of the lanthanides sheds light on the selective toxicity mechanisms associated with critical materials.全基因组毒代基因组学研究镧系元素，揭示了与关键材料相关的选择性毒性机制。
Proc Natl Acad Sci U S A. 2021 May 4;118(18). doi: 10.1073/pnas.2025952118.
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The reference genome sequence of Saccharomyces cerevisiae: then and now.酿酒酵母的参考基因组序列：过去与现在。
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Localization of telomeres and telomere-associated proteins in telomerase-negative Saccharomyces cerevisiae.端粒及端粒相关蛋白在端粒酶阴性酿酒酵母中的定位
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Hybridization, introgression, and linkage evolution.杂交、基因渐渗与连锁进化。
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Chromosome size-dependent control of meiotic reciprocal recombination in Saccharomyces cerevisiae: the role of crossover interference.酿酒酵母中减数分裂相互重组的染色体大小依赖性控制：交叉干涉的作用。
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Ctf19p: A novel kinetochore protein in Saccharomyces cerevisiae and a potential link between the kinetochore and mitotic spindle.Ctf19p：酿酒酵母中一种新型的动粒蛋白，也是动粒与有丝分裂纺锤体之间的潜在联系。
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Pulsed-field gel electrophoresis.脉冲场凝胶电泳
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Ion tolerance of Saccharomyces cerevisiae lacking the Ca2+/CaM-dependent phosphatase (calcineurin) is improved by mutations in URE2 or PMA1.缺乏Ca2+/钙调神经磷酸酶（钙调磷酸酶）的酿酒酵母的离子耐受性通过URE2或PMA1中的突变得到改善。
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Cloning and physical mapping of the EcoRI fragments of the giant linear plasmid SCP1.巨大线性质粒SCP1的EcoRI片段的克隆与物理图谱构建
J Bacteriol. 1998 May;180(10):2796-9. doi: 10.1128/JB.180.10.2796-2799.1998.

本文引用的文献

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The nucleotide sequence of the HIS4 region of yeast.酵母HIS4区域的核苷酸序列。
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Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor.用于加工酵母前体α因子所需的赖氨酸-精氨酸裂解内肽酶的假定结构基因的分离。
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Molecular cloning of the GAL80 gene from Saccharomyces cerevisiae and characterization of a gal80 deletion.来自酿酒酵母的GAL80基因的分子克隆及gal80缺失的表征
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Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis.通过脉冲场梯度凝胶电泳分离酵母染色体大小的DNA。
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酿酒酵母基因组110千碱基分辨率的物理图谱。

Physical map of the Saccharomyces cerevisiae genome at 110-kilobase resolution.

作者信息

Link A J, Olson M V

机构信息

Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110.

出版信息

Genetics. 1991 Apr;127(4):681-98. doi: 10.1093/genetics/127.4.681.

DOI:10.1093/genetics/127.4.681
PMID:2029969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1204396/
Abstract

A physical map of the Saccharomyces cerevisiae genome is presented. It was derived by mapping the sites for two restriction endonucleases, SfiI and NotI, each of which recognizes an 8-bp sequence. DNA-DNA hybridization probes for genetically mapped genes and probes that span particular SfiI and NotI sites were used to construct a map that contains 131 physical landmarks--32 chromosome ends, 61 SfiI sites and 38 NotI sites. These landmarks are distributed throughout the non-rDNA component of the yeast genome, which comprises 12.5 Mbp of DNA. The physical map suggests that those genes that can be detected and mapped by standard genetic methods are distributed rather uniformly over the full physical extent of the yeast genome. The map has immediate applications to the mapping of genes for which single-copy DNA-DNA hybridization probes are available.

摘要

本文展示了酿酒酵母基因组的物理图谱。它是通过绘制两种限制性内切酶SfiI和NotI的位点而得到的，这两种酶各自识别一个8碱基对的序列。用于遗传定位基因的DNA-DNA杂交探针以及跨越特定SfiI和NotI位点的探针被用来构建一个包含131个物理标记的图谱——32个染色体末端、61个SfiI位点和38个NotI位点。这些标记分布在酵母基因组的非rDNA组分中，该组分包含12.5兆碱基对的DNA。物理图谱表明，那些可以通过标准遗传方法检测和定位的基因在酵母基因组的整个物理范围内分布相当均匀。该图谱可直接应用于那些有单拷贝DNA-DNA杂交探针可用的基因的定位。