Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Québec, Canada.
Biol Psychol. 2010 May;84(2):325-9. doi: 10.1016/j.biopsycho.2010.03.013. Epub 2010 Mar 17.
Impact of body weight loss, body fat distribution and the nutritional status on the cortisol response to the Trier Social Stress Test (TSST) was investigated in this study. Fifty-one men (17 non-obese, 20 abdominally obese and 14 reduced obese) and 28 women (12 non-obese, 10 peripherally obese and 6 reduced obese) were subjected to the TSST in fed and fasted states. The TSST response was determined using salivary cortisol measurements. The nutritional status (being fed or fasted) had no effect on the cortisol levels during and following the TSST. Reduced obese men exhibited lower cortisol levels than non-obese men. Cortisol levels in obese men were not different from those of non-obese and reduced obese subjects. In women, there was no significant difference between groups. These finding suggest that weight status in men influences cortisol reactivity to a psychological stress and the different responses seen among genders could be linked to the different fat distributions that characterize men and women.
本研究旨在探讨体重减轻、体脂分布和营养状况对皮质醇对特里尔社会应激测试（TSST）反应的影响。51 名男性（17 名非肥胖、20 名腹部肥胖和 14 名减肥肥胖）和 28 名女性（12 名非肥胖、10 名外周肥胖和 6 名减肥肥胖）在进食和禁食状态下接受了 TSST。使用唾液皮质醇测量来确定 TSST 反应。营养状况（进食或禁食）对 TSST 期间和之后的皮质醇水平没有影响。减肥肥胖男性的皮质醇水平低于非肥胖男性。肥胖男性的皮质醇水平与非肥胖和减肥肥胖受试者没有差异。在女性中，各组之间没有显著差异。这些发现表明，男性的体重状况会影响皮质醇对心理压力的反应，而男性和女性之间的不同反应可能与男女特有的不同脂肪分布有关。
