人乳腺囊肿液中的诱变剂。
Mutagens in human breast cyst fluid.
作者信息
Scott W N, Miller W R
机构信息
University Department of Surgery, Royal Infirmary, Edinburgh, UK.
出版信息
J Cancer Res Clin Oncol. 1991;117(3):254-8. doi: 10.1007/BF01625434.
Abstract
Cyst fluids aspirated from patients presenting with palpable cysts of the breast were analysed for mutagenic activity, as determined by the Ames test. Of the 439 women studied, 9.6% had mutagen-positive fluids. There was no obvious relationship between the presence of mutagen-positive fluids and clinical or epidemiological details of the women from which they were obtained. Preliminary characterisation of the mutagenic activity suggested that the responsible agents have diverse chemical properties.
摘要
对从有可触及乳腺囊肿的患者中抽取的囊肿液进行了致突变活性分析，采用艾姆斯试验进行测定。在研究的439名女性中，9.6%的人囊肿液致突变呈阳性。致突变阳性囊肿液的存在与获取囊肿液的女性的临床或流行病学细节之间没有明显关系。对致突变活性的初步表征表明，致病因子具有多种化学性质。
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本文引用的文献
1
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Cancer Res. 1981 Jan;41(1):105-7.
2
Mutagenic activity in nipple aspirates of human breast fluid.
Cancer Res. 1980 Jan;40(1):188-9.
3
Cation levels in human breast cyst fluid.
Clin Oncol. 1981 Dec;7(4):388-90.
4
Two-stage model for carcinogenesis: Epidemiology of breast cancer in females.致癌作用的两阶段模型：女性乳腺癌的流行病学
J Natl Cancer Inst. 1980 Sep;65(3):559-69.
5
Classification of human breast cysts according to electrolyte and androgen conjugate composition.根据电解质和雄激素结合物成分对人乳腺囊肿进行分类。
Clin Oncol. 1983 Sep;9(3):227-32.
6
7
Physiologic, biochemical, and cytologic aspects of nipple aspirate fluid.乳头抽吸液的生理、生化及细胞学方面
Breast Cancer Res Treat. 1986;8(1):7-19. doi: 10.1007/BF01805919.
8
Alpha 1-antitrypsin, transferrin, alkaline phosphatase, phosphohexoseisomerase and gamma-glutamyltransferase in breast cyst fluid.
Tumori. 1985 Apr 30;71(2):135-40. doi: 10.1177/030089168507100208.
9
The mutagenic activity of human breast secretions.
J Cancer Res Clin Oncol. 1990;116(5):499-502. doi: 10.1007/BF01613001.
10
Evaluation of a breast cyst fluid protein detectable in the plasma of breast carcinoma patients.对一种可在乳腺癌患者血浆中检测到的乳腺囊肿液蛋白质的评估。
Ann Surg. 1977 Mar;185(3):279-85. doi: 10.1097/00000658-197703000-00005.
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