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类固醇激素在人乳腺囊肿液中的积聚。

Steroid hormone accumulation in human breast cyst fluid.

作者信息

Bradlow H L, Rosenfeld R S, Kream J, Fleisher M, O'Connor J, Schwartz M K

出版信息

Cancer Res. 1981 Jan;41(1):105-7.

PMID:7448749
Abstract

Elevated concentrations of peptide hormones have been described previously in human breast fluid. In the current study, the levels of cortisol, progesterone, testosterone, dihydrotestosterone, androsterone, androsterone sulfate, dehydroisoandrosterone, dehydroisoandrosterone sulfate, estradiol, estrone, estradiol sulfate, and estrone sulfate were measured. The levels of the four 17-ketosteroids and the two estrogen sulfates were markedly elevated over the plasma level, while that of the other compounds was the same or only slightly higher than the plasma levels of the same compounds.

摘要

此前已有研究报道人乳汁中肽类激素浓度升高。在本研究中,测定了皮质醇、孕酮、睾酮、双氢睾酮、雄酮、硫酸雄酮、脱氢表雄酮、硫酸脱氢表雄酮、雌二醇、雌酮、硫酸雌二醇和硫酸雌酮的水平。四种17 - 酮类固醇和两种雌激素硫酸盐的水平显著高于血浆水平,而其他化合物的水平与相同化合物的血浆水平相同或仅略高。

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Steroid hormone accumulation in human breast cyst fluid.类固醇激素在人乳腺囊肿液中的积聚。
Cancer Res. 1981 Jan;41(1):105-7.
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引用本文的文献

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Lower Serum Levels of Uric Acid in Uterine Fibroids and Fibrocystic Breast Disease Patients in Dongying City, China.中国东营市子宫肌瘤和纤维囊性乳腺病患者血清尿酸水平较低
Iran J Public Health. 2016 May;45(5):596-605.
2
Hormones in Dairy Foods and Their Impact on Public Health - A Narrative Review Article.乳制品中的激素及其对公众健康的影响——一篇叙述性综述文章。
Iran J Public Health. 2015 Jun;44(6):742-58.
3
Factors affecting dehydroepiandrosterone sulphate levels in human breast secretions.
Breast Cancer Res Treat. 1981;1(3):267-72. doi: 10.1007/BF01806267.
4
Oestrone sulphate, adipose tissue, and breast cancer.硫酸雌酮、脂肪组织与乳腺癌
Breast Cancer Res Treat. 1985;6(1):75-87. doi: 10.1007/BF01806013.
5
Epidemiology and endocrinology of benign breast disease.良性乳腺疾病的流行病学与内分泌学
Breast Cancer Res Treat. 1985;6(1):5-36. doi: 10.1007/BF01806008.
6
beta-Glucuronidase levels in patients with fibrocystic breast disease.纤维囊性乳腺病患者的β-葡萄糖醛酸酶水平。
Breast Cancer Res Treat. 1986;8(3):217-22. doi: 10.1007/BF01807334.
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Estrogen sulfates: biological and ultrastructural responses and metabolism in MCF-7 human breast cancer cells.硫酸雌激素:MCF-7人乳腺癌细胞中的生物学和超微结构反应及代谢
Breast Cancer Res Treat. 1986;8(3):233-40. doi: 10.1007/BF01807336.
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The endocrine basis of benign breast disorders.良性乳腺疾病的内分泌基础。
World J Surg. 1989 Nov-Dec;13(6):674-9. doi: 10.1007/BF01658413.
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Immunologic and steroid binding properties of the GCDFP-24 protein isolated from human breast gross cystic disease fluid.从人乳腺大囊性病液中分离出的GCDFP - 24蛋白的免疫学及类固醇结合特性。
Breast Cancer Res Treat. 1990 Oct;16(3):253-60. doi: 10.1007/BF01806333.
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Mutagens in human breast cyst fluid.人乳腺囊肿液中的诱变剂。
J Cancer Res Clin Oncol. 1991;117(3):254-8. doi: 10.1007/BF01625434.