澳大利亚南部的多发性基底细胞癌与HLA频率

Multiple basal cell carcinomas and HLA frequencies in southern Australia.

作者信息

Czarnecki D, Lewis A, Nicholson I, Tait B

机构信息

Repatriation General Hospital, Heidelberg, Australia.

出版信息

J Am Acad Dermatol. 1991 Apr;24(4):559-61. doi: 10.1016/0190-9622(91)70082-d.

DOI:10.1016/0190-9622(91)70082-d

PMID:2033130

Abstract

An association between HLA-DR1 and the development of multiple basal cell carcinomas was detected in southern Australia. A reduction in HLA-DR4 was found in patients with basal cell carcinoma compared with a local control group. The relative risk for HLA-DR1 was 2.1, which was lower than that for persons in farther countries from the equator.

摘要

在澳大利亚南部检测到HLA - DR1与多发性基底细胞癌的发生之间存在关联。与当地对照组相比，基底细胞癌患者体内HLA - DR4有所减少。HLA - DR1的相对风险为2.1，低于赤道附近其他国家人群的相对风险。