肥厚性颈椎延长：临床与组织学相关性
Hypertrophic cervical elongation: clinical and histological correlations.
作者信息
Ibeanu Okechukwu A, Chesson Ralph R, Sandquist Dane, Perez Javier, Santiago Kerri, Nolan Thomas E
机构信息
Johns Hopkins University, Baltimore, MD, USA.
出版信息
Int Urogynecol J. 2010 Aug;21(8):995-1000. doi: 10.1007/s00192-010-1131-3. Epub 2010 Mar 24.
INTRODUCTION AND HYPOTHESIS
The objective of this study is to define the diagnosis of hypertrophic cervical elongation clinically and to perform histochemical and histological evaluations of patients with and without hypertrophic cervical elongation.
METHODS
This prospective study was conducted at Louisiana State University between December 2005 and May 2008. Fourteen women with cervical elongation and 28 women without prolapse were studied.
RESULTS
The amounts of elastin, collagen, and smooth muscle did not differ between study and control groups. Estrogen and progesterone receptor content in cervical elongation were elevated compared to the cervix of women without prolapse. Hypertrophic cervical elongation was defined as the difference between point C and point D of the Pelvic Organ Prolapse Quantification system greater than 8 cm.
CONCLUSIONS
Estrogen and progesterone receptor levels are greater in women with hypertrophic cervical elongation compared with a normal cervix.
引言与假设
本研究的目的是从临床上明确肥厚性宫颈延长的诊断，并对有和没有肥厚性宫颈延长的患者进行组织化学和组织学评估。
方法
这项前瞻性研究于2005年12月至2008年5月在路易斯安那州立大学进行。研究了14名有宫颈延长的女性和28名没有子宫脱垂的女性。
结果
研究组和对照组之间的弹性蛋白、胶原蛋白和平滑肌含量没有差异。与没有子宫脱垂的女性的宫颈相比，宫颈延长中的雌激素和孕激素受体含量升高。肥厚性宫颈延长被定义为盆腔器官脱垂定量系统中C点和D点之间的差异大于8厘米。
结论
与正常宫颈相比，肥厚性宫颈延长的女性中雌激素和孕激素受体水平更高。
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