Cao Yuan, Chen Ji-Jun, Tan Ning-Hua, Oberer Lukas, Wagner Trixie, Wu Yong-Ping, Zeng Guang-Zhi, Yan He, Wang Qiang
Department of Chinese Materia Medica Analysis, China Pharmaceutical University, Nanjing 210009, People's Republic of China.
Bioorg Med Chem Lett. 2010 Apr 15;20(8):2456-60. doi: 10.1016/j.bmcl.2010.03.016. Epub 2010 Mar 7.
Six selaginellin derivatives, including three new analogues selaginellins D-F (1-3), were isolated from the EtOAc extract of the whole plant of Selaginella pulvinata (Hook. et Grev.) Maxim. Their structures were determined on the basis of extensive physical and chemical evidence. Compounds 1 and 4 demonstrated antifungal activities against Candida albicans; compounds 4-6 exhibited significant antibacterial activity against Staphylococcus aureus.
从垫状卷柏（Hook. et Grev.）Maxim.全草的乙酸乙酯提取物中分离得到6种卷柏素衍生物，包括3个新类似物卷柏素D - F（1 - 3）。基于广泛的物理和化学证据确定了它们的结构。化合物1和4对白色念珠菌表现出抗真菌活性；化合物4 - 6对金黄色葡萄球菌表现出显著的抗菌活性。
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