University of Innsbruck, Institute of Ion Physics and Applied Physics, Innsbruck, Austria.
J Am Soc Mass Spectrom. 2010 Jun;21(6):1037-44. doi: 10.1016/j.jasms.2010.02.006. Epub 2010 Feb 10.
We present the unprecedented capability to identify and quantify volatile organic compounds (VOCs) by means of proton transfer reaction time-of-flight (PTR-TOF) mass spectrometry on-line with high time resolution. A mass resolving power of 4000-5000 and a mass accuracy of 2.5 ppm allow for the unambiguous sum-formula identification of hydrocarbons (HCs) and oxygenated VOCs (OVOCs). Test masses measured over an 11-wk period are very precise (SD < 3.4 ppm) and the mass resolving power shows good stability (SD < 5%). Based on a 1 min time resolution, we demonstrate a detection limit in the low pptv range featuring a dynamic range of six orders of magnitude. Sub-ppbv VOC concentrations are analyzed within a second; sub-pptv detection limits are achieved within a few tens of minutes. We present a thorough characterization of our recently developed PTR-TOF system and address application fields for the new instrument.
我们展示了一种前所未有的能力，即通过质子转移反应飞行时间（PTR-TOF）质谱联用仪以高时间分辨率在线识别和定量挥发性有机化合物（VOCs）。4000-5000 的质量分辨率和 2.5 ppm 的质量精度允许对碳氢化合物（HCs）和含氧挥发性有机化合物（OVOCs）进行明确的总和式识别。在 11 周的测量时间内，测试质量非常精确（SD < 3.4 ppm），质量分辨率显示出良好的稳定性（SD < 5%）。基于 1 分钟的时间分辨率，我们展示了在低 pptv 范围内的检测极限，具有六个数量级的动态范围。亚 ppbv 的 VOC 浓度可在一秒内进行分析；亚 pptv 检测极限可在几十分钟内实现。我们对最近开发的 PTR-TOF 系统进行了全面的表征，并介绍了该新仪器的应用领域。
