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唾液中乙型肝炎病毒 DNA 与慢性乙型肝炎感染患儿：唾液作为水平传播潜在途径的意义。

Hepatitis B virus DNA in saliva from children with chronic hepatitis B infection: implications for saliva as a potential mode of horizontal transmission.

机构信息

Department of Paediatrics, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.

出版信息

Pediatr Infect Dis J. 2010 May;29(5):465-7. doi: 10.1097/INF.0b013e3181d8e009.

DOI:10.1097/INF.0b013e3181d8e009
PMID:20335824
Abstract

To explore the mechanism of horizontal transmission of hepatitis B virus (HBV) among children, we investigated the quantitative relationship between HBV in saliva and blood from 46 children with chronic hepatitis B. We found high levels of HBV DNA in saliva of HBeAg (+) children, suggesting saliva as a vehicle for horizontal transmission of HBV among children.

摘要

为了探究乙型肝炎病毒（HBV）在儿童中水平传播的机制，我们调查了 46 名慢性乙型肝炎儿童的唾液和血液中 HBV 的定量关系。我们发现 HBeAg(+)儿童的唾液中 HBV DNA 水平较高，提示唾液可能是儿童间 HBV 水平传播的媒介。

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