University of Washington, Department of Mechanical Engineering, Seattle, Washington 98195, USA.
J Biophotonics. 2010 Jun;3(5-6):385-407. doi: 10.1002/jbio.200900087.
In modern endoscopy, wide field of view and full color are considered necessary for navigating inside the body, inspecting tissue for disease and guiding interventions such as biopsy or surgery. Current flexible endoscope technologies suffer from reduced resolution when device diameter shrinks. Endoscopic procedures today, using coherent fiber-bundle technology on the scale of 1 mm, are performed with such poor image quality that the clinician's vision meets the criteria for legal blindness. Here, we review a new and versatile scanning fiber-imaging technology and describe its implementation for ultrathin and flexible endoscopy. This scanning fiber endoscope (SFE) or catheterscope enables high-quality, laser-based, video imaging for ultrathin clinical applications, while also providing new options for in vivo biological research of subsurface tissue and high resolution fluorescence imaging.
在现代内窥镜检查中,宽视场和全彩色被认为是在体内导航、检查疾病组织和引导活检或手术等介入所必需的。目前的柔性内窥镜技术在设备直径缩小时会降低分辨率。目前,在 1 毫米的尺度上使用相干光纤束技术进行内窥镜手术,其图像质量非常差,以至于临床医生的视力符合法定失明的标准。在这里,我们回顾了一种新的通用扫描光纤成像技术,并描述了其在超薄和灵活内窥镜中的实现。这种扫描光纤内窥镜(SFE)或导管镜能够实现高质量的基于激光的视频成像,适用于超薄的临床应用,同时还为体内亚表面组织的生物学研究和高分辨率荧光成像提供了新的选择。