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注意缺陷多动障碍严重程度作为自闭症谱系障碍(ASD)儿童认知任务表现的预测指标。

ADHD severity as a predictor of cognitive task performance in children with Autism Spectrum Disorder (ASD).

作者信息

Mansour Rosleen, Ward Anthony R, Lane David M, Loveland Katherine A, Aman Michael G, Jerger Susan, Schachar Russell J, Pearson Deborah A

机构信息

McGovern Medical School, University of Texas Health Science Center at Houston, United States.

Rice University, United States.

出版信息

Res Dev Disabil. 2021 Apr;111:103882. doi: 10.1016/j.ridd.2021.103882. Epub 2021 Feb 3.

Abstract

BACKGROUND

In recent years, a number of studies have begun to explore the nature of Attention-Deficit/Hyperactivity Disorder (ADHD) in children with Autism Spectrum Disorder (ASD). In this study, we examined the relationship between both symptoms of ADHD and symptoms of ASD on cognitive task performance in a sample of higher-functioning children and adolescents with ASD. Participants completed cognitive tasks tapping aspects of attention, impulsivity/inhibition, and immediate memory.

AIMS

We hypothesized that children with ASD who had higher levels of ADHD symptom severity would be at higher risk for poorer sustained attention and selective attention, greater impulsivity/disinhibition, and weaker memory.

METHODS AND PROCEDURES

The sample included 92 children (73 males) diagnosed with ASD (Mean Age = 9.41 years; Mean Full Scale IQ = 84.2).

OUTCOMES AND RESULTS

Using regression analyses, more severe ADHD symptomatology was found to be significantly related to weaker performance on tasks measuring attention, immediate memory, and response inhibition. In contrast, increasing severity of ASD symptomatology was not associated with higher risk of poorer performance on any of the cognitive tasks assessed.

CONCLUSIONS AND IMPLICATIONS

These results suggest that children with ASD who have more severe ADHD symptoms are at higher risk for impairments in tasks assessing attention, immediate memory, and response inhibition-similar to ADHD-related impairments seen in the general pediatric population. As such, clinicians should assess various aspects of cognition in pediatric patients with ASD in order to facilitate optimal interventional and educational planning.

摘要

背景

近年来,一些研究已开始探索自闭症谱系障碍(ASD)儿童中注意力缺陷多动障碍(ADHD)的本质。在本研究中,我们在一组高功能ASD儿童和青少年样本中,考察了ADHD症状与ASD症状对认知任务表现的关系。参与者完成了涉及注意力、冲动性/抑制及即时记忆方面的认知任务。

目的

我们假设,ADHD症状严重程度较高的ASD儿童在持续注意力和选择性注意力较差、冲动性/抑制性较强及记忆力较弱方面风险更高。

方法与程序

样本包括92名被诊断为ASD的儿童(73名男性)(平均年龄 = 9.41岁;平均智商 = 84.2)。

结果

通过回归分析发现,更严重的ADHD症状与在测量注意力、即时记忆和反应抑制的任务中表现较弱显著相关。相比之下,ASD症状严重程度增加与所评估的任何认知任务中表现较差的较高风险均无关联。

结论与启示

这些结果表明,具有更严重ADHD症状的ASD儿童在评估注意力、即时记忆和反应抑制的任务中出现损伤的风险更高——类似于普通儿科人群中所见的与ADHD相关的损伤。因此,临床医生应评估ASD儿科患者认知的各个方面,以便促进最佳的干预和教育规划。

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