Institute of Materia Medica, Shandong Academy of Medical Sciences, Jinan 250062, China.
J Nat Med. 2010 Jul;64(3):358-61. doi: 10.1007/s11418-010-0407-8. Epub 2010 Mar 27.
Ten flavonoids were isolated from the ethyl acetate-soluble fraction of the ethanolic extract of the seeds of Trigonella foenum-graecum and their structures were elucidated on the basis of spectroscopic methods to be 5,7,3'-trihydroxy-5'-methoxylisoflavone (1), biochanin A (2), formononetin (3), irilone (4), tricin (5), daidzein (6), calycosin (7), orientin-2''-O-p-trans-coumarate (8), vitexin-2''-O-p-trans-coumarate (9), and tricin-7-O-beta-D: -glucopyranoside (10). Compounds 1 and 8 are new flavonoids, and 8 and 9 strongly promoted 2BS cell proliferation induced by H(2)O(2).
从胡芦巴种子的乙醇提取物的乙酸乙酯可溶部分中分离得到 10 种类黄酮，根据光谱方法阐明了它们的结构，分别为 5,7,3'-三羟基-5'-甲氧基异黄酮（1）、大豆素 A（2）、芒柄花素（3）、伊尔洛内（4）、三叶草素（5）、大豆苷元（6）、金雀异黄素（7）、橙皮素-2''-O-对反式肉桂酸酯（8）、荭草苷-2''-O-对反式肉桂酸酯（9）和三叶草素-7-O-β-D：-吡喃葡萄糖苷（10）。化合物 1 和 8 为新的类黄酮，化合物 8 和 9 强烈促进 H2O2 诱导的 2BS 细胞增殖。
