Burr B, Burr F A
Biology Department, Brookhaven National Laboratory, Upton, NY 11973.
Trends Genet. 1991 Feb;7(2):55-60. doi: 10.1016/0168-9525(91)90232-F.
Molecular mapping is rapidly being extended to more species as one result of the current emphasis on genome initiatives. The choice of the population used for mapping can have important consequences on the efficiency and accessibility of the mapping information. Recombinant inbred lines offer certain advantages over other mapping populations for many species. These more or less permanent populations permit many geneticists to contribute to the mapping effort and to profit from each other's work. Recombinant inbred lines are used extensively in mouse genetics and have been used in maize to compile a detailed molecular map.
由于当前对基因组计划的重视,分子图谱正迅速扩展到更多物种。用于图谱构建的群体选择可能会对图谱信息的效率和可获取性产生重要影响。对于许多物种而言,重组自交系相对于其他图谱构建群体具有某些优势。这些或多或少永久性的群体使许多遗传学家能够为图谱构建工作做出贡献,并从彼此的工作中受益。重组自交系在小鼠遗传学中被广泛使用,并且已在玉米中用于编制详细的分子图谱。