International Prevention Research Institute, Lyon, France.
J Occup Environ Med. 2010 Apr;52(4):399-406. doi: 10.1097/JOM.0b013e3181d5e355.
To perform a quantitative estimate of the proportion of cancers attributable to occupational exposures in France in 2000.
Exposure data for established carcinogens were obtained from a 1994 survey and other sources. Relative risks for 23 exposure-cancer combinations were derived from meta-analyses and pooled analyses.
A total of 4335 cases of cancer among men (2.7% of all cancers) and 403 cases among women (0.3% of all cancers) were attributed to occupational exposures. Asbestos, polycyclic aromatic hydrocarbons, and chromium VI were the main occupational carcinogens in men, and asbestos and involuntary smoking were the main carcinogens in women. Corresponding proportions for cancer deaths were 4.0% and 0.6% in men and women, respectively. Lung cancer represented 75% of deaths attributable to occupational exposures.
Our estimates are comparable with those obtained for other countries in studies based on similar methodology.
定量估计 2000 年法国归因于职业暴露的癌症比例。
从 1994 年的一项调查和其他来源获取了已确定致癌物的暴露数据。通过荟萃分析和汇总分析得出了 23 种暴露-癌症组合的相对风险。
共有 4335 例男性癌症（占所有癌症的 2.7%）和 403 例女性癌症（占所有癌症的 0.3%）归因于职业暴露。石棉、多环芳烃和六价铬是男性的主要职业致癌物，而石棉和被动吸烟是女性的主要致癌物。相应的癌症死亡比例分别为男性 4.0%和女性 0.6%。肺癌占职业暴露所致死亡的 75%。
我们的估计与其他国家基于类似方法的研究得出的估计值相当。
