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J Child Psychol Psychiatry. 2009 Jan;50(1-2):63-71. doi: 10.1111/j.1469-7610.2008.01978.x.
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Genes Brain Behav. 2008 Jun;7(4):435-46. doi: 10.1111/j.1601-183X.2007.00368.x. Epub 2008 Jan 22.
6
The genetic and environmental origins of learning abilities and disabilities in the early school years.学前期学习能力与学习障碍的遗传及环境根源。
Monogr Soc Res Child Dev. 2007;72(3):vii, 1-144. doi: 10.1111/j.1540-5834.2007.00439.x.
7
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9
Twins' Early Development Study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behavior problems from childhood through adolescence.双胞胎早期发育研究(TEDS):一项从童年到青春期对语言、认知和行为问题进行的多变量纵向基因调查。
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学习能力和障碍的遗传学:来自英国的最新进展及中国研究的可能方向。2008 年。

Genetics of learning abilities and disabilities: recent developments from the UK and possible directions for research in China. 2008.

出版信息

Behav Genet. 2010 May;40(3):297-305. doi: 10.1007/s10519-010-9355-z.

DOI:10.1007/s10519-010-9355-z
PMID:20358396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4091916/
Abstract

It is exciting to witness the birth of behavioral genetics in China at a time when the field of genetics is exploding with new discoveries. We begin by discussing the potential for Chinese researchers to sidestep the false starts of previous genetic research on behavior and to become leaders rather than followers in behavioral genetics research. Using learning abilities and disabilities as an example, the rest of the paper considers ways in which quantitative genetic research can go beyond the nature versus nurture question to ask more interesting questions about genetics and psychology. These include the relationship between the normal and abnormal, longitudinal analyses of stability and change, and multivariate analyses of heterogeneity and homogeneity. The most important way to go beyond the rudimentary question about nature versus nurture is to identify the genes responsible for genetic influence on behavior. We briefly describe our quantitative genetic findings and genome-wide association studies of learning ability from the UK Twins Early Development Study (TEDS). It seems a safe prediction that the fast pace of genetic discoveries will continue and will increasingly affect the field of psychology in China and the rest of the world.

摘要

在中国遗传学领域不断涌现新发现之际,见证行为遗传学的诞生令人兴奋。我们首先讨论了中国研究人员避开先前关于行为的遗传学研究错误开始的可能性,并在行为遗传学研究中成为领导者而不是追随者。本文以学习能力和障碍为例,考虑了定量遗传学研究如何超越先天与后天的问题,提出关于遗传学和心理学更有趣的问题。这些问题包括正常与异常之间的关系、稳定性和变化的纵向分析,以及异质性和同质性的多变量分析。超越先天与后天这一基本问题的最重要方法是确定对行为具有遗传影响的基因。我们简要描述了我们从英国双胞胎早期发展研究(TEDS)中得出的关于学习能力的定量遗传学发现和全基因组关联研究。可以肯定地预测,遗传发现的快速步伐将继续下去,并将越来越多地影响中国和世界其他地区的心理学领域。