Akershus University College, Lillestrøm, Norway.
Public Health Nutr. 2010 Sep;13(9):1472-7. doi: 10.1017/S1368980010000650. Epub 2010 Apr 1.
To assess the prevalence of enlarged thyroid volume (Tvol) in Saharawi refugee children, and their urinary iodine concentration (UIC), and to identify possible sources of excess iodine intake.
A cross-sectional survey was performed during January-February 2007. Tvol was measured by ultrasound and iodine concentration was analysed in casual urine samples, in household drinking water and in milk samples from household livestock.
The study was undertaken in four refugee camps in the Algerian desert.
The subjects were 421 Saharawi children, 6-14 years old.
Enlarged Tvol was found in 56 % (Tvol-for-age) and 86 % (Tvol-for-body-surface-area) of the children. The median (25th percentile-75th percentile, P25-P75) UIC was 565 (357-887) microg/l. The median (P25-P75) iodine concentration in household drinking water was 108 (77-297) microg/l. None of the children had UIC below 100 microg/l, 16 % had UIC between 100 and 299 microg/l, and 84 % had UIC above 300 microg/l. There was a positive association between Tvol and whether the household possessed livestock.
The children are suffering from endemic goitre and high UIC caused probably by an excessive intake of iodine. The excessive iodine intakes probably originate from drinking water and milk.
评估撒哈拉难民儿童甲状腺容积(Tvol)增大的患病率,以及他们的尿碘浓度(UIC),并确定碘过量摄入的可能来源。
2007 年 1 月至 2 月进行了一项横断面调查。通过超声测量 Tvol,分析家庭饮用水和家庭牲畜奶样中的碘浓度。
该研究在阿尔及利亚沙漠的四个难民营进行。
421 名 6-14 岁的撒哈拉儿童。
56%(Tvol-年龄)和 86%(Tvol-体表面积)的儿童甲状腺容积增大。UIC 的中位数(25 百分位数-75 百分位数,P25-P75)为 565(357-887)μg/l。家庭饮用水的中位数(P25-P75)碘浓度为 108(77-297)μg/l。没有儿童的 UIC 低于 100μg/l,16%的儿童 UIC 为 100-299μg/l,84%的儿童 UIC 高于 300μg/l。甲状腺容积与家庭是否拥有牲畜之间存在正相关关系。
儿童患有地方性甲状腺肿和 UIC 高,可能是由于碘摄入过多。过量的碘摄入可能来自饮用水和牛奶。