Berger R, Le Coniat M, Derré J, Vecchione D
Unité INSERM U 301, Institut de Génétique Moléculaire, Paris, France.
Cancer Genet Cytogenet. 1991 May;53(1):113-7. doi: 10.1016/0165-4608(91)90122-b.
Six patients with non-Hodgkin malignant lymphoma (NHL) in a series of 151 cases showed partial deletion of chromosome 2 when studied cytogenetically. Three had deletions of bands 2p14-p22 and three others had a deletion of bands 2q22-q24 in common. The deletions were associated with other abnormalities in each case and were not associated with a particular subtype of NHL. These deletions are secondary, apparently nonrandom, new abnormalities associated with NHL.
在151例非霍奇金恶性淋巴瘤（NHL）患者系列中，6例经细胞遗传学研究显示2号染色体部分缺失。其中3例缺失2p14 - p22带，另外3例共同缺失2q22 - q24带。这些缺失在每例中均与其他异常相关，且与特定的NHL亚型无关。这些缺失是与NHL相关的继发性、明显非随机的新异常。
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