Brook J D, Knight S J, Roberts S H, Harley H G, Walsh K V, Rundle S A, Freyne K, Koch M C, Epstein N D, Wieringa B
Institute of Medical Genetics, University of Wales College of Medicine, Heath Park, Cardiff, UK.
Hum Genet. 1991 May;87(1):65-72. doi: 10.1007/BF01213095.
We have constructed and analysed somatic cell hybrids from cell lines containing balanced reciprocal translocations involving chromosome 19 and providing two new breakpoints on 19q. These and other hybrids have been tested with a series of markers from 19q to enhance the existing map. Several new cloned DNA sequences that map to 19q13.3-19qter are reported; the locus D19Z1 has been analysed by CHEF gel electrophoresis.
我们构建并分析了来自含有涉及19号染色体的平衡相互易位的细胞系的体细胞杂种，这些易位在19q上提供了两个新的断点。已使用一系列来自19q的标记对这些杂种及其他杂种进行了测试，以完善现有的图谱。报告了几个定位于19q13.3 - 19qter的新克隆DNA序列；已通过钳位均匀电场凝胶电泳分析了基因座D19Z1。
