Faculty of Health Sciences, Department of Physical Therapy, Recanati School for Community Health Professions, Ben-Gurion University of the Negev, P.O.B. 653, 84105, Beer Sheva, Israel.
Rheumatol Int. 2010 Sep;30(11):1533-6. doi: 10.1007/s00296-010-1494-2. Epub 2010 Apr 7.
The aim of the study was to compare the prevalence of radiographic hand osteoarthritis (OA) and its association with age, sex, body mass index in two ethnic groups, Russian and Buryats who reside in the same geographic area. It was a cross-sectional observational study. The study population comprised ethnic Russians (N = 572) and Buryats (N = 327) from the Barguzinsky District of the Buryat Republic, Russian Federation. OA was evaluated in 14 joints of the left hand according to Kellgren and Lawrence's grading system. A diagnosis of OA was determined by the number of affected joints and by the presence of at least one affected joint. Statistical analyses included prevalence estimation, linear and logistic regressions, and chi(2) tests. Our major finding was that individuals of different ethnic groups, residing in the same location, have similar prevalence and severity of radiographic hand OA. Considering the results of our previous study, where we found significant differences in the prevalence and severity of hand OA between the Russian samples (same ethnicity) with diverse places of residence, we conclude that environmental factors play an important role in the development of hand OA.
本研究旨在比较居住在同一地理区域的俄罗斯族和布里亚特族两种族裔人群的手部放射学骨关节炎（OA）患病率及其与年龄、性别、体重指数的相关性。这是一项横断面观察性研究。研究人群包括来自俄罗斯联邦布里亚特共和国巴尔古津斯基区的俄罗斯族（N=572）和布里亚特族（N=327）。根据 Kellgren 和 Lawrence 分级系统评估左手 14 个关节的 OA。OA 的诊断通过受累关节数量和至少一个受累关节的存在来确定。统计分析包括患病率估计、线性和逻辑回归以及卡方检验。我们的主要发现是，居住在同一地点的不同族裔人群手部放射学 OA 的患病率和严重程度相似。考虑到我们之前的研究结果，我们发现不同居住地的俄罗斯人群（同一种族）手部 OA 的患病率和严重程度存在显著差异，我们得出结论，环境因素在手 OA 的发展中起着重要作用。
