Department of Physical Therapy, Recanati School for Community Health Professions, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Osteoarthritis Cartilage. 2010 Jun;18(6):803-9. doi: 10.1016/j.joca.2010.02.006. Epub 2010 Feb 19.
The aim of the study was to evaluate the prevalence and pattern of radiographic hand osteoarthritis (OA) and its association with age, sex, body mass index (BMI), and place of residence in five Russian community-based samples.
Cross-sectional observational study: The study population comprised ethnic Russians [821 males and 1076 females, aged 18-90 (mean 46.2+/-15.3)], living in five different geographic areas. OA was evaluated for 14 joints of the left hand according to the Kellgren and Lawrence grading scheme. Statistical analyses included prevalence estimation, logistic and generalized model regressions, and chi(2) tests.
We present extensive data on the prevalence of radiographic hand OA in a total Russian sample. After the age of 65, 98.5% of males and 96.8% of females had at least one affected joint. In individuals younger than 50, OA was most prevalent in the metacarpophalangeal joints, and after age 50, was most prevalent in the distal interphalangeal joints. Prevalence of hand OA was significantly higher in males than in females in ages 35-50. After adjustment for age, age(2) and place of residence, there were no associations between prevalence or severity of hand OA and BMI.
Significant differences in prevalence and severity of hand OA were found between the Russian samples living in different geographic areas. Additional studies are needed to discover the mechanism defining the association between places of residence and development of hand OA.
本研究旨在评估五种俄罗斯社区样本中手部影像学骨关节炎（OA）的流行率和模式，及其与年龄、性别、体重指数（BMI）和居住地的关系。
横断面观察性研究：研究人群包括俄罗斯裔人群[821 名男性和 1076 名女性，年龄 18-90 岁（平均 46.2±15.3 岁）]，居住在五个不同的地理区域。根据 Kellgren 和 Lawrence 分级方案评估左手 14 个关节的 OA。统计分析包括患病率估计、逻辑和广义模型回归以及卡方检验。
我们提供了俄罗斯总人群手部影像学 OA 患病率的广泛数据。男性在 65 岁以后，98.5%，女性在 96.8%至少有一个受累关节。在 50 岁以下的个体中，OA 最常见于掌指关节，而在 50 岁以后，最常见于远侧指间关节。在 35-50 岁年龄组，男性的手部 OA 患病率明显高于女性。调整年龄、年龄平方和居住地后，手部 OA 的患病率或严重程度与 BMI 之间无关联。
生活在不同地理区域的俄罗斯样本之间，手部 OA 的流行率和严重程度存在显著差异。需要进一步研究以发现定义居住地与手部 OA 发展之间关系的机制。
