Kalichman L, Korosteshevsky M, Batsevich V, Kobyliansky E
Department of Physical Therapy, Recanati School for Community Health Professions, Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O.B. 653, Beer Sheva 84105, Israel.
Homo. 2011 Aug;62(4):280-7. doi: 10.1016/j.jchb.2011.04.003. Epub 2011 May 11.
The aim of this study was to evaluate whether geographic location and climatic factors are associated with prevalence and severity of radiographic hand osteoarthritis (OA) in several samples of the same ethnicity. The total sample included 2079 ethnic Russians (900 males and 1179 females), belonging to 7 samples from different geographic locations in the former USSR. Places of residence were characterized by latitude, longitude, altitude and climatic parameters (mean temperatures, humidity, and daylight duration of January and July). Radiographs of the left hand were obtained from each individual. Osteoarthritis (OA) was evaluated in 14 hand joints according to Kellgren and Lawrence's grading system. OA was characterized by the presence of at least one affected joint and its severity by the number of affected joints (NAJ). Statistical analysis included prevalence estimation, polynomial and logistic regressions, ANOVA and correlation analyses. Prevalence of hand OA and NAJ were significantly associated with latitude and altitude and with most climatic parameters (except the inter-seasonal temperature amplitude and the mean atmospheric pressure of January and July). The highest correlations of hand OA prevalence were found with altitude (r=0.29, p<0.001), annual precipitation (r=-0.26, p<0.001) and the mean temperatures of July (r=0.26, p<0.001). The highest correlations of NAJ were found with altitude (r=0.51, p<0.001), mean humidity in January (r=-0.44, p<0.001) and the mean day duration in January (r=0.0.37, p<0.001). The present study demonstrates that the differences in prevalence and severity of radiographic hand OA among Russian samples are most likely dependent on climatic conditions in the place of residence.
本研究的目的是评估地理位置和气候因素是否与同一民族的多个样本中手部X线骨关节炎（OA）的患病率及严重程度相关。总样本包括2079名俄罗斯族人（900名男性和1179名女性），来自前苏联不同地理位置的7个样本。居住地的特征包括纬度、经度、海拔和气候参数（1月和7月的平均温度、湿度和日照时长）。从每个个体获取左手的X线片。根据Kellgren和Lawrence分级系统对14个手部关节进行骨关节炎（OA）评估。OA的特征为至少存在一个受累关节，其严重程度由受累关节数量（NAJ）表示。统计分析包括患病率估计、多项式和逻辑回归、方差分析及相关性分析。手部OA患病率和NAJ与纬度、海拔以及大多数气候参数（1月和7月的季节间温度幅度及平均大气压力除外）显著相关。手部OA患病率与海拔（r = 0.29，p < 0.001）、年降水量（r = -0.26，p < 0.001）和7月平均温度（r = 0.26，p < 0.001）的相关性最高。NAJ与海拔（r = 0.51，p < 0.001）、1月平均湿度（r = -0.44，p < 0.001）和1月平均日照时长（r = 0.37，p < 0.001）的相关性最高。本研究表明，俄罗斯样本中手部X线OA患病率和严重程度的差异很可能取决于居住地的气候条件。
