Faculty of Applied Chemistry and Material Science, Politehnica University of Bucharest, 1-7 Polizu Street, 011061 Bucharest, Romania.
J Mater Sci Mater Med. 2010 Jul;21(7):2237-42. doi: 10.1007/s10856-010-4076-7. Epub 2010 Apr 7.
Our purpose was obtaining and characterizing a complex composite system with multifunctional role: bone graft material and hyperthermia generator necessary for bone cancer therapy. The designed system was a magnetite enriched collagen/hydroxyapatite composite material, obtained by a co-precipitation method. Due to the applied electromagnetic field the magnetite will induce hyperthermia and cause tumoral cell apoptosis. The complex bone graft system was characterised by XRD, FTIR and SEM, while the hyperthermia was quantify by measuring the temperature increase due to the applied alternative electromagnetical field.
骨移植物材料和骨癌治疗所需的热疗发生器。设计的系统是一种通过共沉淀法获得的富磁铁矿的胶原/羟基磷灰石复合材料。由于施加的电磁场，磁铁矿将诱导热疗并导致肿瘤细胞凋亡。通过 XRD、FTIR 和 SEM 对复合骨移植物系统进行了表征，而通过测量施加交变电磁场引起的温度升高来定量热疗。
