Medicine, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Ullmann 1223, Bronx, NY 10461, USA.
Clin Microbiol Rev. 2010 Apr;23(2):253-73. doi: 10.1128/CMR.00076-09.
All humans are colonized with Candida species, mostly Candida albicans, yet some develop diseases due to Candida, among which genitourinary manifestations are extremely common. The forms of genitourinary candidiasis are distinct from each other and affect different populations. While vulvovaginal candidiasis affects mostly healthy women, candiduria occurs typically in elderly, hospitalized, or immunocompromised patients and in neonates. Despite its high incidence and clinical relevance, genitourinary candidiasis is understudied, and therefore, important questions about pathogenesis and treatment guidelines remain to be resolved. In this review, we summarize the current knowledge about genitourinary candidiasis.
所有人都被念珠菌属物种定植，其中大多数为白色念珠菌，但有些人会因念珠菌而患病，其中泌尿生殖系统表现极为常见。泌尿生殖系统念珠菌病的形式彼此不同，影响的人群也不同。虽然外阴阴道念珠菌病主要影响健康女性，但尿念珠菌病通常发生在老年、住院或免疫功能低下的患者以及新生儿中。尽管泌尿生殖系统念珠菌病发病率高且具有重要的临床意义，但研究不足，因此，关于发病机制和治疗指南的重要问题仍有待解决。在这篇综述中，我们总结了目前关于泌尿生殖系统念珠菌病的知识。
