Department of Psychiatry, University of California San Diego, La Jolla, CA 92093-0804, USA.
Ann Behav Med. 2010 Jun;39(3):222-31. doi: 10.1007/s12160-010-9181-9.
Although objective and subjective indicators of socioeconomic status (SES) are linked to cardiovascular disease (CVD), little is known about their relationship to endothelial dysfunction, which often precedes CVD.
This study examined how objective and subjective SES relate to brachial artery flow-mediated dilation (FMD).
FMD was assessed in 72 healthy adults (mean age 36 years). The MacArthur Scale of Subjective Social Status assessed perceived social standing in the USA (SSS-USA) and local community (SSS-Community). Objective SES measures included income and the Hollingshead Two-Factor Index of Social Position (education, occupation).
Adjusted regressions revealed that SSS-Community positively correlated with FMD (p < 0.05) and explained 8% of the variance. No other SES measures were significant for FMD. The association between FMD and SSS-Community remained significant (p < 0.01) after adjustment for objective SES and other covariates.
Lower subjective social status in one's community may be linked to CVD via impaired vasodilation.
尽管客观和主观的社会经济地位（SES）指标与心血管疾病（CVD）有关，但对于它们与内皮功能障碍的关系知之甚少，内皮功能障碍通常先于 CVD 发生。
本研究探讨了客观和主观 SES 与肱动脉血流介导的扩张（FMD）的关系。
在 72 名健康成年人（平均年龄 36 岁）中评估了 FMD。麦克阿瑟社会地位主观量表评估了在美国（SSS-USA）和当地社区（SSS-Community）的感知社会地位。客观 SES 测量指标包括收入和霍林斯黑德两因素社会地位指数（教育、职业）。
调整后的回归显示，社区主观社会地位与 FMD 呈正相关（p < 0.05），解释了 8%的方差。其他 SES 测量指标与 FMD 无关。在调整客观 SES 和其他协变量后，FMD 与 SSS-Community 之间的关联仍然显著（p < 0.01）。
一个人所在社区的较低主观社会地位可能通过血管舒张受损与 CVD 相关。
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