van Dijk P T, Dippel D W, Habbema J D
Center for Clinical Decision Analysis, Erasmus University, Rotterdam, The Netherlands.
J Am Geriatr Soc. 1991 Jun;39(6):603-10. doi: 10.1111/j.1532-5415.1991.tb03602.x.
The evidence on survival in dementia is summarized. There are no reliable data on survival after onset of dementia or after first contact with medical services. People with dementia in outpatient clinics and nursing homes have 2-year survival rates of 75% (range 60%-95%) and 50% (range 30%-65%), respectively. Differences in survival between patients with senile dementia of the Alzheimer's type (SDAT) and multi infarct dementia (MID) are small. Women in nursing homes have a better prognosis than men (2-year survival rates, 60% vs 40%). Dementia patients have a considerable excess mortality when compared to the vital statistics. There is no evidence for improvement of survival rates during recent decades. Recommendations for future studies are made.
总结了痴呆症患者生存情况的相关证据。关于痴呆症发病后或首次接触医疗服务后的生存率，目前尚无可靠数据。门诊诊所和养老院中的痴呆症患者2年生存率分别为75%（范围60%-95%）和50%（范围30%-65%）。阿尔茨海默型老年痴呆症（SDAT）患者和多发梗死性痴呆（MID）患者在生存率上的差异较小。养老院中的女性患者预后比男性更好（2年生存率分别为60%和40%）。与人口动态统计数据相比，痴呆症患者的死亡率显著偏高。近几十年来，没有证据表明生存率有所提高。文中还给出了对未来研究的建议。
