Hier D B, Warach J D, Gorelick P B, Thomas J
Department of Neurology, Michael Reese Hospital and Medical Center, Chicago, Ill 60616.
Arch Neurol. 1989 Nov;46(11):1213-6. doi: 10.1001/archneur.1989.00520470073030.
Duration of survival from time of first evaluation was studied in 61 patients with clinically diagnosed Alzheimer's disease (senile dementia of the Alzheimer type [SDAT]) and 34 patients with clinically diagnosed multi-infarct dementia (MID). Duration of survival did not differ significantly between MID and SDAT. However, since MID patients were younger at onset, MID patients had a lower life quotient than SDAT patients. Race, sex, and age at onset were not predictive of survival in SDAT. History of hypertension, elevated systolic blood pressure, lower scores on tests of Block Designs, and Logico-Grammatical Comprehension predicted shorter survival in SDAT. Age at onset and race were not predictive of survival in MID. Male sex, lower educational attainment, as well as low scores on tests of Logico-Grammatical Comprehension, Digit Span, Naming, Verbal Fluency, and receptive vocabulary, predicted shorter survival in MID.
对61例临床诊断为阿尔茨海默病（阿尔茨海默型老年痴呆症[SDAT]）的患者和34例临床诊断为多发梗死性痴呆（MID）的患者，研究了自首次评估起的生存时长。MID和SDAT患者的生存时长无显著差异。然而，由于MID患者起病时年龄较小，MID患者的生活质量指数低于SDAT患者。种族、性别和起病年龄不能预测SDAT患者的生存情况。高血压病史、收缩压升高、在积木图案测试和逻辑语法理解测试中得分较低，可预测SDAT患者生存时间较短。起病年龄和种族不能预测MID患者的生存情况。男性、受教育程度较低，以及在逻辑语法理解、数字广度、命名、言语流畅性和接受性词汇测试中得分较低，可预测MID患者生存时间较短。
