Mölsä P K, Marttila R J, Rinne U K
Department of Neurology, University of Turku, Finland.
Acta Neurol Scand. 1995 Mar;91(3):159-64. doi: 10.1111/j.1600-0404.1995.tb00426.x.
Long-term survival was examined for 218 patients with Alzheimer's disease (AD) and 115 patients with multi-infarct dementia (MID). The 14-year survival rate for AD was 2.4% versus an expected rate of 16.6%, and for MID 1.7% versus 13.3% expected. MID showed a more malignant natural course than AD. Men carried a less favourable survival prognosis than women, both in AD and MID: the relative risk of dying for women was half that for men in both diseases. In MID, advanced disability indicated a relative risk of dying over twice as high. In both diseases the risk of death was substantially higher in the event of occurrence of primitive reflexes.
对218例阿尔茨海默病（AD）患者和115例多梗死性痴呆（MID）患者的长期生存率进行了研究。AD的14年生存率为2.4%，而预期生存率为16.6%；MID的14年生存率为1.7%，预期生存率为13.3%。MID的自然病程比AD更具恶性。在AD和MID中，男性的生存预后均不如女性：在这两种疾病中，女性死亡的相对风险均为男性的一半。在MID中，晚期残疾表明死亡的相对风险高出两倍多。在这两种疾病中，出现原始反射时死亡风险显著更高。
