Administration of Clinical Research and Teaching, School of Stomatology, the Fourth Military Medical University, Xi'an PR China.
BMC Public Health. 2010 Apr 16;10:196. doi: 10.1186/1471-2458-10-196.
Although several studies have reported the direct cost of oral cancer (OC), little research has invested the factors that could influence the costs of OC patient. This study analyzes the epidemiological characteristics and the direct cost of OC. More specifically, the study examines the relationship between patients' medical costs and influencing factors of epidemiology.
All patients encountered from January 2007 to December 2007 at the School of Stomatology of the Fourth Military Medical University (FMMU) in China with diagnosis of oral cancer have been selected. Medical hospitalization days (MHD) and cost per patient (CPP) of the samples have been calculated for different patient groups, and the results have been compared using statistical methods.
A total of 456 oral cancer patients have been selected in this study. The epidemical characteristics are as follows: female/male 176/280; squamous cell carcinoma (SCC)/adenocarcinoma/sarcoma/lymphoma/other types 246/127/40/27/16; stage I/II/III/IV 90/148/103/115; smoker/non-smoker 136/320; rural/urban patients 82/374. Of all the patients, 82.24% were over 40 years of age. Rural patients were significantly younger than urban patients. SCC was the majority histology in older patients, while sarcoma was more common in younger patients. 372 of the patients received treatment and 84 gave up any treatment after diagnosis. Treatment cost accounted for majority of the payment. The CPP and MHD of patients in late clinical stage were higher than that of patient in early stage.
Gender, smoking habit and age older than 40 years are the epidemiological risk factors for oral cancer. Lack of medicare, smoking habit, late clinical stage and SCC are the high economic factors for patient medical cost.
尽管已有几项研究报告了口腔癌（OC）的直接成本，但很少有研究涉及可能影响 OC 患者成本的因素。本研究分析了 OC 的流行病学特征和直接成本。更具体地说，该研究检查了患者医疗费用与流行病学影响因素之间的关系。
本研究选取了 2007 年 1 月至 2007 年 12 月在中国第四军医大学口腔医学院就诊并诊断为口腔癌的所有患者。对不同患者组的样本进行了医疗住院日（MHD）和每位患者的费用（CPP）的计算，并使用统计方法进行了比较。
本研究共选取了 456 例口腔癌患者。流行病学特征如下：女性/男性 176/280；鳞状细胞癌（SCC）/腺癌/肉瘤/淋巴瘤/其他类型 246/127/40/27/16；I/II/III/IV 期 90/148/103/115；吸烟者/非吸烟者 136/320；农村/城市患者 82/374。所有患者中，82.24%的患者年龄超过 40 岁。农村患者明显比城市患者年轻。老年患者中 SCC 是主要组织学类型，而年轻患者中肉瘤更为常见。372 例患者接受了治疗，84 例患者在诊断后放弃了任何治疗。治疗费用占支付费用的大部分。晚期临床阶段患者的 CPP 和 MHD 高于早期阶段患者。
性别、吸烟习惯和 40 岁以上年龄是口腔癌的流行病学危险因素。缺乏医疗保险、吸烟习惯、晚期临床阶段和 SCC 是患者医疗费用高的经济因素。
