Department of Oral Medicine and Pathology, King's College Dental Institute, Bessemer Rd., London SE5 9RS, UK.
Oral Oncol. 2010 Jun;46(6):407-10. doi: 10.1016/j.oraloncology.2010.02.015. Epub 2010 Apr 18.
This review presents data on incidence, mortality, survival and trends on cancers of the lip, oral cavity and oropharynx using available recent data sources around the world. Oral and pharyngeal cancer, grouped together is the sixth most common cancer in the world. The review focuses primarily on prevalence of people still alive after an oral cancer diagnosis. In the world, there is close to a three quarter of a million people who previously had oral cancer and alive at 5years after diagnosis. The proportion alive at 5years is lower in less developed countries compared to earlier years. Within in Europe highest prevalence at 5years is seen in Western Europe. Our prevention strategies for this high risk group should include offering smoking cessation and other risk reduction measures. Smoking cessation in particular improves prognostic outcomes reducing the risk of secondary disease by approximately 2-3-fold.
本综述介绍了利用世界各地现有最新数据源得出的关于唇癌、口腔癌和口咽癌的发病率、死亡率、生存率和趋势数据。口腔和咽癌合在一起是全球第六大常见癌症。本综述主要关注的是癌症诊断后仍存活的患者的流行率。在全球范围内，有近 25 万人曾患有口腔癌，并且在诊断后 5 年内仍然存活。与前些年相比，欠发达国家中 5 年生存率较低。在欧洲，5 年生存率最高的是西欧。我们针对这一高危人群的预防策略应包括提供戒烟和其他降低风险的措施。戒烟尤其可以改善预后结果，使继发性疾病的风险降低约 2-3 倍。
