Institute for Lung Diseases and Tuberculosis, Clinical Centre of Serbia, Belgrade, Serbia.
Pathol Oncol Res. 2011 Mar;17(1):175-9. doi: 10.1007/s12253-010-9272-8. Epub 2010 Apr 21.
We present a case of large cell lung carcinoma in sixty-one year old male with typical lung cancer symptoms but unusual radiological presentation and immunophenotype. Tumor morphological finding related to its radiological finding was suggestive for large cell lymphoma or carcinoma, but its immunophenotype made confusion for pathological diagnosis. No p53 mutations were detected in genetic investigation. Multidisciplinary diagnostic approach to some tumors is useful for their final diagnosis.
我们报告了一例 61 岁男性的大细胞肺癌病例,其具有典型的肺癌症状,但影像学表现和免疫表型不典型。肿瘤形态学发现与影像学表现相关,提示为大细胞淋巴瘤或癌,但免疫表型使病理诊断出现混淆。遗传研究未检测到 p53 突变。对某些肿瘤进行多学科诊断方法有助于其最终诊断。