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大细胞肺癌伴不常见的影像学特征、免疫表型和遗传学发现。

Large cell lung carcinoma with unusual imaging feature, immunophenotype and genetic finding.

机构信息

Institute for Lung Diseases and Tuberculosis, Clinical Centre of Serbia, Belgrade, Serbia.

出版信息

Pathol Oncol Res. 2011 Mar;17(1):175-9. doi: 10.1007/s12253-010-9272-8. Epub 2010 Apr 21.

DOI:10.1007/s12253-010-9272-8
PMID:20405348
Abstract

We present a case of large cell lung carcinoma in sixty-one year old male with typical lung cancer symptoms but unusual radiological presentation and immunophenotype. Tumor morphological finding related to its radiological finding was suggestive for large cell lymphoma or carcinoma, but its immunophenotype made confusion for pathological diagnosis. No p53 mutations were detected in genetic investigation. Multidisciplinary diagnostic approach to some tumors is useful for their final diagnosis.

摘要

我们报告了一例 61 岁男性的大细胞肺癌病例，其具有典型的肺癌症状，但影像学表现和免疫表型不典型。肿瘤形态学发现与影像学表现相关，提示为大细胞淋巴瘤或癌，但免疫表型使病理诊断出现混淆。遗传研究未检测到 p53 突变。对某些肿瘤进行多学科诊断方法有助于其最终诊断。

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Immunohistochemistry for assessment of pulmonary and pleural neoplasms: a review and update.用于评估肺和胸膜肿瘤的免疫组织化学：综述与更新
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Bronchopulmonary neuroendocrine tumors.支气管肺神经内分泌肿瘤
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Prognostic significance of p53 and Ki-67 antigen expression in surgically treated non-small cell lung cancer: immunocytochemical detection with imprint cytology.p53和Ki-67抗原表达在手术治疗的非小细胞肺癌中的预后意义：印片细胞学免疫细胞化学检测
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