O'Connor J P A, O'Moráin C A, Vargo J J
Department of Gastroenterology, Adelaide and Meath Hospital, Trinity College Dublin, Dublin, Ireland.
Digestion. 2010;82(2):124-6. doi: 10.1159/000285698. Epub 2010 Apr 21.
The use of propofol for sedation in endoscopy may allow for better quality of sedation, quicker recovery and facilitate greater throughput in endoscopy units. The cost-effectiveness and utility of propofol sedation for endoscopic procedures is contingent on the personnel and resources required to carry out the procedure. Computer-based platforms are based on the patients response to stimulation and physiologic parameters. They offer an appealing means of delivering safe and effective doses of propofol. One such means is the bispectral index where continuous EEG recordings are used to assess the degree of sedation. Another is the closed-loop target-controlled system where a set of physical parameters, such as muscle relaxation and auditory-evoked potential, determine a level of medication appropriate to achieve sedation. Patient-controlled platforms may also be used. These electronic adjuncts may help endoscopists who wish to adopt propofol sedation to change current practices with greater confidence.
在内镜检查中使用丙泊酚进行镇静可能会带来更好的镇静质量、更快的恢复，并有助于提高内镜检查单位的吞吐量。丙泊酚镇静用于内镜手术的成本效益和实用性取决于实施该手术所需的人员和资源。基于计算机的平台基于患者对刺激的反应和生理参数。它们提供了一种给予安全有效剂量丙泊酚的有吸引力的方法。一种这样的方法是双谱指数，其中连续脑电图记录用于评估镇静程度。另一种是闭环靶控系统，其中一组物理参数，如肌肉松弛和听觉诱发电位，确定适合实现镇静的药物水平。也可以使用患者自控平台。这些电子辅助设备可能有助于希望采用丙泊酚镇静的内镜医师更有信心地改变当前的做法。
