Department and Graduate Institute of Forensic Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Int J Legal Med. 2011 Jan;125(1):33-7. doi: 10.1007/s00414-009-0414-z. Epub 2010 Apr 29.
A 13 X-chromosomal short tandem repeat (STR) multiplex system (DXS6807, DXS8378, DSX9902, DXS7132, DXS9898, DXS6809, DXS6789, DXS7424, DXS101, GATA172D05, HPRTB, DXS8377, and DXS7423) was tested on 1,037 DNA samples from eight population groups currently living in Taiwan. Different distributions of the allelic frequencies in different populations were presented. DXS8377 and DXS101 were the two most polymorphic loci in these eight populations, whereas DXS7423 was the least informative marker in most of the populations studied. The genetic distances between the populations and the constructed phylogenetic tree revealed a long genetic distance between Asian and Caucasian populations as well as isolation of the Tao population. The phylogenetic tree grouped populations into clusters compatible with their ethnogeographic relationships. This 13 X-chromosomal short tandem repeat multiplex system offers a considerable number of polymorphic patterns in different populations. This system can be useful in forensic identification casework and ethnogeographic research.
一项 13 个 X 染色体短串联重复（STR）多重检测系统（DXS6807、DXS8378、DSX9902、DXS7132、DXS9898、DXS6809、DXS6789、DXS7424、DXS101、GATA172D05、HPRTB、DXS8377 和 DXS7423）在当前居住在台湾的 8 个人群的 1037 个 DNA 样本中进行了测试。不同人群的等位基因频率分布呈现出不同的特征。在这 8 个人群中，DXS8377 和 DXS101 是两个最具多态性的基因座，而 DXS7423 在大多数研究人群中是最不具信息量的标记。人群之间的遗传距离和构建的系统发生树揭示了亚洲和高加索人群之间的遗传距离较长，以及 Tao 人群的隔离。系统发生树将人群聚类为与其种族地理关系相匹配的聚类。这项 13 个 X 染色体短串联重复多重检测系统在不同人群中提供了大量的多态性模式。该系统可用于法医鉴定和种族地理研究。
