University of Western Sydney, Senior Staff Specialist, Campbelltown Hospital, Campbelltown, 2560 NSW, Australia.
Curr Opin Allergy Clin Immunol. 2010 Jun;10(3):246-51. doi: 10.1097/ACI.0b013e32833973fb.
This paper reviews current concepts in our understanding of oral allergy or pollen-food syndrome. As technology has improved, much more accurate profiling of food allergic individuals is now possible, resulting in more precise diagnosis, elucidation of cross reactivity patterns and more helpful prediction of risk of anaphylaxis.
The identification and characterization of various ubiquitous plant proteins have led to greater understanding of food cross reactive reactions. Newer diagnostic techniques utilizing purified and recombinant allergens are available for more precise diagnosis and clinical profiling of patients presenting with food allergy.
In-vitro screening of food allergic patients with large panels of allergens will change the accuracy of diagnosis resulting in better management. Allergens are now available for use in the allergist's office to improve diagnostic accuracy of skin tests in patients presenting with plant-food allergy. Knowledge of the specific sensitization of individual patients has consequences for both risk assessment and dietary management.
本文综述了目前我们对口腔过敏或花粉-食物综合征的理解。随着技术的进步，现在可以更准确地对食物过敏个体进行分析，从而更精确地诊断、阐明交叉反应模式，并更好地预测过敏反应的风险。
对各种普遍存在的植物蛋白的鉴定和特征分析，使人们对食物交叉反应有了更深入的了解。利用纯化和重组变应原的新技术，可用于更精确地诊断和临床分析出现食物过敏的患者。
利用过敏原的大面板对食物过敏患者进行体外筛选，将提高诊断的准确性，从而改善管理。现在，变应原可用于过敏科医生的办公室，以提高对出现植物-食物过敏的患者进行皮肤试验的诊断准确性。了解个体患者的具体致敏情况，对风险评估和饮食管理都有影响。
