Centre for Health Economics and Policy Analysis, McMaster University, Hamilton, Ont.
CMAJ. 2010 Jun 15;182(9):E362-72. doi: 10.1503/cmaj.081165. Epub 2010 May 3.
Gaps continue to exist between research-based evidence and clinical practice. We surveyed health care providers in 10 low- and middle-income countries about their use of research-based evidence and examined factors that may facilitate or impede such use.
We surveyed 1499 health care providers practising in one of four areas relevant to the Millennium Development Goals (prevention of malaria, care of women seeking contraception, care of children with diarrhea and care of patients with tuberculosis) in each of China, Ghana, India, Iran, Kazakhstan, Laos, Mexico, Pakistan, Senegal and Tanzania.
The proportion of respondents who reported that research was likely to change their clinical practice if performed and published in their own country (84.6% and 86.0% respectively) was higher than the proportion who reported the same about research and publications from their region (66.4% and 63.1%) or from high-income countries (55.8% and 55.5%). Respondents who were most likely to report that the use of research-based evidence led to changes in their practice included those who reported using clinical practice guidelines in paper format (odds ratio [OR] 1.54, 95% confidence interval [CI] 1.03-2.28), using scientific journals from their own country in paper format (OR 1.70, 95% CI 1.26-2.28), viewing the quality of research performed in their country as above average or excellent (OR 1.93, 95% CI 1.16-3.22); trusting systematic reviews of randomized controlled trials (OR 1.59, 95% CI 1.08-2.35); and having easy access to the Internet (OR 1.90, 95% CI 1.19-3.02).
Locally conducted or published research has played an important role in changing the professional practice of health care providers surveyed in low- and middle-income countries. Increased investments in local research, or at least in locally adapted publications of research-based evidence from other settings, are therefore needed. Although access to the Internet was viewed as a significant factor in whether research-based evidence led to concrete changes in practice, few respondents reported having easy access to the Internet. Therefore, efforts to improve Internet access in clinical settings need to be accelerated.
研究证据与临床实践之间仍存在差距。我们调查了 10 个中低收入国家的卫生保健提供者,了解他们对研究证据的使用情况,并研究了可能促进或阻碍这种使用的因素。
我们调查了中国、加纳、印度、伊朗、哈萨克斯坦、老挝、墨西哥、巴基斯坦、塞内加尔和坦桑尼亚,每个国家的四个与千年发展目标相关的领域(预防疟疾、妇女避孕护理、儿童腹泻护理和结核病患者护理)中,1499 名卫生保健提供者。
报告称,如果在本国进行和发表研究,研究可能会改变他们的临床实践的受访者比例(分别为 84.6%和 86.0%)高于报告称来自本地区(分别为 66.4%和 63.1%)或高收入国家(分别为 55.8%和 55.5%)的研究和出版物会改变他们的临床实践的受访者比例。最有可能报告研究证据的使用导致他们实践发生变化的受访者包括那些报告使用纸质格式的临床实践指南(比值比[OR]1.54,95%置信区间[CI]1.03-2.28)、使用本国的纸质科学期刊(OR1.70,95%CI1.26-2.28)、认为本国进行的研究质量高于平均水平或优秀(OR1.93,95%CI1.16-3.22);信任随机对照试验的系统评价(OR1.59,95%CI1.08-2.35);以及能够轻松访问互联网(OR1.90,95%CI1.19-3.02)。
在中低收入国家进行的或发表的研究在改变接受调查的卫生保健提供者的专业实践方面发挥了重要作用。因此,需要增加对本地研究的投资,或者至少增加对来自其他环境的基于研究证据的本地改编出版物的投资。尽管受访者认为能够访问互联网是研究证据是否导致实践发生具体变化的一个重要因素,但很少有受访者表示能够轻松访问互联网。因此,需要加快努力改善临床环境中的互联网接入。