Pediatric Preventive Cardiology Department, Isfahan Cardiovascular, Research Centre, Isfahan University of Medical Sciences, PO Box 81465-1148, Isfahan, Iran.
J Am Coll Nutr. 2009 Oct;28(5):601-10. doi: 10.1080/07315724.2009.10719792.
To determine the long-term effect of a randomized controlled trial of a dairy-rich diet on generalized and abdominal obesity, as well as on the components of the metabolic syndrome, among obese prepubescent children.
This trial was conducted among a population-based sample of 120 obese prepubescent children who were randomly assigned to 3 groups of equal number. In addition to attending 6 consecutive monthly family-centered education sessions about healthy lifestyle, an isocaloric dairy-rich diet (>800 mg ca/d) was recommended to the children of one group (DR: dairy-rich diet), the second group was placed on a caloric-restricted regimen (ER: energy-restricted), and the third group received no additional recommendation (C: controls). The groups were then followed-up twice a year for 3 years.
The mean age of the children was 5.6 +/- 0.5 years. Of 120 participants, 95 (75%) completed the study; the DR group had the highest retention rate. In all groups, body mass index-standard deviation score (BMI-SDS) and waist circumference decreased significantly after the 6-month trial, but had a sustained significant rise during the follow-up period to the end of the study; however, in the DR group, this rise was significantly lower than in the 2 other groups. After the 6-month trial, in all groups, serum triglycerides (TG) and insulin levels decreased, and serum high-density lipoprotein cholesterol (HDL-C) level and homeostasis model assessment of insulin resistance (HOMA-R) increased. In the DR group, the TG, insulin and HOMA-R levels remained significantly lower than baseline until the 12-month follow-up.
We suggest that in addition to lifestyle changes, an isocaloric diet rich in dairy products may be a well-accepted regimen and can be a safe and practical strategy for weight control in young, overweight children.
确定富含乳制品的饮食对肥胖青春期前儿童的全身性和腹部肥胖以及代谢综合征成分的长期影响。
本试验在一个基于人群的肥胖青春期前儿童样本中进行,将 120 名肥胖儿童随机分为 3 组,每组人数相等。除了参加 6 次连续的以家庭为中心的关于健康生活方式的教育课程外,还向一组儿童(DR:富含乳制品的饮食)推荐等热量的富含乳制品的饮食(>800mg Ca/d),第二组采用热量限制饮食(ER:能量限制),第三组不给予额外建议(C:对照组)。然后,在 3 年内每年对这些组进行两次随访。
儿童的平均年龄为 5.6±0.5 岁。120 名参与者中,95 名(75%)完成了研究;DR 组的保留率最高。在所有组中,体重指数标准差评分(BMI-SDS)和腰围在 6 个月试验后显著下降,但在随访期间持续显著上升,直至研究结束;然而,在 DR 组中,这种上升明显低于其他 2 组。在 6 个月的试验后,所有组的血清甘油三酯(TG)和胰岛素水平降低,而血清高密度脂蛋白胆固醇(HDL-C)水平和胰岛素抵抗的稳态模型评估(HOMA-R)增加。在 DR 组中,TG、胰岛素和 HOMA-R 水平在 12 个月的随访中仍显著低于基线。
我们建议,除了生活方式的改变外,富含乳制品的等热量饮食可能是一种可接受的饮食方案,可以作为控制年轻超重儿童体重的安全实用策略。