Neonatal Services, The Royal Women's Hospital, Melbourne, Australia.
Pediatrics. 2010 Jun;125(6):e1340-7. doi: 10.1542/peds.2009-1510. Epub 2010 May 3.
The goal was to define reference ranges for pulse oxygen saturation (Spo(2)) values in the first 10 minutes after birth for infants who received no medical intervention in the delivery room.
Infants were eligible if a member of the research team was available to record Spo(2) immediately after birth. Infants were excluded if they received supplemental oxygen or any type of assisted ventilation. Spo(2) was measured with a sensor applied to the right hand or wrist as soon as possible after birth; data were collected every 2 seconds.
We studied 468 infants and recorded 61650 Spo(2) data points. The infants had a mean + or - SD gestational age of 38 + or - 4 weeks and birth weight of 2970 + or - 918 g. For all 468 infants, the 3rd, 10th, 50th, 90th, and 97th percentile values at 1 minute were 29%, 39%, 66%, 87%, and 92%, respectively, those at 2 minutes were 34%, 46%, 73%, 91%, and 95%, and those at 5 minutes were 59%, 73%, 89%, 97%, and 98%. It took a median of 7.9 minutes (interquartile range: 5.0-10 minutes) to reach a Spo(2) value of >90%. Spo(2) values for preterm infants increased more slowly than those for term infants. We present percentile charts for all infants, term infants of > or = 37 weeks, preterm infants of 32 to 36 weeks, and extremely preterm infants of <32 weeks.
These data represent reference ranges for Spo(2) in the first 10 minutes after birth for preterm and term infants.
本研究旨在为产房内未接受任何医学干预的新生儿出生后 10 分钟内的脉搏血氧饱和度（Spo₂）值定义参考范围。
如果研究团队的成员能够在出生后立即记录 Spo₂，则符合纳入标准。如果新生儿接受了补充氧气或任何类型的辅助通气，则将其排除在外。Spo₂通过在出生后尽快将传感器应用于右手或手腕进行测量；数据每 2 秒收集一次。
我们研究了 468 名婴儿，并记录了 61650 个 Spo₂数据点。这些婴儿的平均（±SD）胎龄为 38±4 周，出生体重为 2970±918g。对于所有 468 名婴儿，1 分钟时第 3、10、50、90 和 97 百分位数分别为 29%、39%、66%、87%和 92%，2 分钟时分别为 34%、46%、73%、91%和 95%，5 分钟时分别为 59%、73%、89%、97%和 98%。中位数达到 Spo₂值>90%的时间为 7.9 分钟（四分位间距：5.0-10 分钟）。早产儿的 Spo₂值增加速度比足月儿慢。我们为所有婴儿、胎龄≥37 周的足月儿、32-36 周的早产儿和<32 周的极早产儿提供了百分位数图表。
这些数据代表了早产儿和足月儿出生后 10 分钟内 Spo₂的参考范围。
