绵羊克隆株ST1464：从苏丹绵羊中分离出的金黄色葡萄球菌厌氧亚种的主要基因型。
Ovine clone ST1464: a predominant genotype of Staphylococcus aureus subsp. anaerobius isolated from sheep in Sudan.
作者信息
Elbir Haitham, Feil Edward J, Drancourt Michel, Roux Véronique, El Sanousi Sulieman M, Eshag Mona, Colque-Navarro Patricia, Kühn Inger, Flock Jan-Ingmar
机构信息
Tropical Medicine Research Institute, Khartoum, Sudan.
出版信息
J Infect Dev Ctries. 2010 May 1;4(4):235-8. doi: 10.3855/jidc.632.
BACKGROUND
The aim of the present study was to examine the phenotypic and genotypic relatedness of 17 Staphylococcus aureus subsp. anaerobius isolates recovered from sheep abscesses in Khartoum state, Sudan, during the period 2007-2008.
METHODOLOGY
This sample was characterised using antibiogram typing, biochemical typing with the commercial PhenePlate system (PhP-CS) and multilocus sequence typing (MLST).
RESULTS
Low levels of resistance were noted to the 11 antimicrobial agents tested. All the isolates corresponded to a single PhP type, and to a single, novel, multilocus sequence type, designated ST1464.
CONCLUSION
These results demonstrate that the vast majority of cases of sheep abscess disease in Khartoum state are caused by a single novel clone of S. aureus subsp. anaerobius.
背景
本研究的目的是检测2007年至2008年期间从苏丹喀土穆州绵羊脓肿中分离出的17株厌氧性金黄色葡萄球菌亚种的表型和基因型相关性。
方法
该样本采用抗菌谱分型、使用商业PhenePlate系统（PhP-CS）进行生化分型以及多位点序列分型（MLST）进行特征分析。
结果
对所测试的11种抗菌药物的耐药水平较低。所有分离株对应单一的PhP型，以及单一的、新的多位点序列型，命名为ST1464。
结论
这些结果表明，喀土穆州绵羊脓肿病的绝大多数病例是由厌氧性金黄色葡萄球菌亚种的单一新克隆引起的。
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